Is Your Relationship … OK?

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1. 

   12 Mar 2026 · 27 min

   Sad Nipple Syndrome: A Booby Baffler

   People are reporting a very strange phenomenon: They say that when their nipples get touched, they feel this weird sinking feeling. People describe it like being homesick, or hung over. Some feel anguish and despair, others call it dread. The condition has a name: "Sad Nipple Syndrome." But how could just touching a nipple set off all of these feelings?? To get to the bottom of this booby baffler, we go deep into the mysteries of anatomy and through a world of hormones and nipple erections. You might never look at your nipples the same way again! Distinguished Professor Barry Komisurak and…

2. 

   26 Feb 2026 · 26 min

   How Do You Get Pregnant With No Vagina?

   UPDATE [June 30, 2026]: If we had our time again we would have produced this episode differently. We got carried away with the wildness of the story, from a scientific perspective, and didn't take time to really think about the fact that this is the story of a 15-year-old, who would have been going through a really difficult time. Many of our listeners rightly pointed this out, and we appreciate it." We have changed some of our language in this episode based on the feedback – we replaced all references to woman to teenager or girl, we cut some moments that we viewed as insensitive, and we…

3. 

   19 Feb 2026 · 54 min

   Brian Can’t Stop Fact-Checking His Mother-in-Law

   We’ve all been there. Feeling stuck with a problem because no one in our life can relate. Or because the one person we need to talk to … won’t. Or can’t. Enter Yowei Shaw and the show Proxy. Proxy is built on a simple idea: no one is ever as alone with their problem as they think. So Yowei brings in a proxy, a perfect stranger, to help her guests work through their dilemma. Today we’re sharing the case of Brian, a journalist whose mother-in-law has Alzheimer's. Even though Brian knows she can’t help misremembering things, he can’t stop losing his patience with her, and with himself. This…

4. 

   29 Jan 2026 · 41 min

   What Do Tear Gas and ICE Raids Do to People?

   Federal agents have descended on Minneapolis in the U.S., and things have gotten chaotic — and deadly. The Trump administration says the agents are there to enforce immigration law, but officers have shot three people so far, killing two, and are using tear gas and smoke on protesters. So today, we’re looking at the potential health impacts of tear gas. We’ll talk about what we do — and don’t — know about potential long-term effects of this stuff. And we’re also looking into research on the mental health effects of immigration raids. We speak to Dr. Jennifer Brown, Dr. Carlee Toddes, and Dr.…

5. 

   22 Jan 2026 · 36 min

   The Secret to Happiness?

   There's claims out there that all kinds of things can make us happy in life, from making money to having kids to buying your dream home. But what actually works?? What does it take to have a happy life?? Professor Bob Waldinger is a psychiatrist at Harvard who has spent more than two decades as the director of this amazing study. It has tracked hundreds of people for decades and is the world's longest scientific study into happiness. So we're gonna find out what a lot of us get wrong in searching for the good life. Where we should be putting our time and attention. And we'll get this huge…

6. 

   15 Jan 2026 · 34 min

   Vaccines: Does Europe Do Them Better?

   The U.S. just made a big change to its vaccine recommendations, cutting back on the number of shots it will routinely recommend for kids. The government says it wants to "better align" with countries like Denmark. But is following Denmark’s lead a fairy tale come true — or a nightmare in slow motion? Plus, we find out what this new schedule could mean for kids’ vaccines in the U.S. We hear from Professor Jens Lundgren and pediatrician and researcher David Higgins. Find our transcript here: https://bit.ly/ScienceVsVaccineSchedules In this episode, we cover: (00:00) The growing turmoil around…

7. 

   4 Jun 2026 · 38 min

   Peptides: The Ultimate Body Hack?

   Peptides are huge right now. Influencers are telling us they can work wonders for all sorts of stuff. Struggling with an annoying injury that won't heal?? Belly fat that's pissing you off? Low energy? Gut issues?? There’s a peptide out there for you. People are buying peptides off the internet and injecting themselves with them, saying it's life changing. But away from the internet hype, there is actually a potential revolution happening in medicine around peptides. So we’re finding out what scientists are excited about here, and we look deeply at the science behind two massive peptides:…

8. 

   28 May 2026 · 41 min

   How Toxic Is the Air You Breathe?

   The Trump administration is rolling back restrictions on air pollution in the U.S., and some experts say this could affect the health of millions of people. And what makes air pollution especially dangerous is that we often can’t see it at all. So today, we’re going back to the story of Ella Kissi-Debrah, a little girl who suddenly got sick and landed in the hospital. In this episode, her mom, Rosamund, takes on the fight to find out what exactly happened to Ella. And the answer has BIG implications — for us all. We’ll hear from Rosamund Adoo-Kissi-Debrah and Professor Stephen Holgate. Find…

9. 

   21 May 2026 · 49 min

   Ibogaine: A Miracle Psychedelic?

   Ibogaine. Fans say this psychedelic is a game changer for treating a bunch of mental health conditions — that even a single trip to your friendly ibogaine clinic could cure you of lifelong struggles with addiction. And recently President Trump signed an executive order fast-tracking research into this psychedelic drug. But how well does it really work? And is it safe?? To find out, we talk to clinical psychologist Dr. Alan Davis and psychiatrist Prof. Paul Glue. Some resources for help with substance use and domestic violence: Substance use and mental health concerns (U.S.): SAMHSA National…

10. 

    13 May 2026 · 32 min

    Hantavirus: How Scary Is It??

    A weird virus has popped up on a cruise ship, and it’s making a bunch of us nervous. It’s a type of hantavirus called Andes virus, and scientists think that it’s infected almost a dozen people so far — three of them have died. And now people are getting off the boat, some of them going into government quarantine, but some of them traveling home. And people are like, wait … this all sounds VERY familiar … from the early days of Covid. So — how scary is this? Could this hantavirus be the next pandemic?? We talk to Prof. Michelle Harkins, Prof. Ann Sheehy and Dr. Neil Vora to find out. Find our…

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