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Season 1, Episode 94 · The Rest Is ScienceNew

Something Weird Is Going On With Placebos

11 Oct 2026 · 49 min

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For the past few decades, something strange has been happening in clinical trials. Painkillers aren't getting worse, but the placebos they're tested against appear to be getting better. In one landmark study, the advantage of pain medication over placebo shrank from 27.3% in 1996 to just 8.9% in 2013. Even stranger? This trend was found almost entirely in American trials.In this episode of The Rest Is Science, Professor Hannah Fry and Michael Stevens (Vsauce) investigate the extraordinary science of the placebo effect; how our expectations influence pain, why belief can change the way our…

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The Rest Is Science

Goalhanger · Tech & Science · English

Join mathematician Professor Hannah Fry and science creator Michael Stevens (Vsauce) as they dig into the weird scientific questions that often go unexplored. Welcome to The Rest Is Science, a show that sits in the fascinating space between what we think we know, and what we actually know. Why do we assume we understand things like time, randomness, or even gravity? Once you start questioning…

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