Equilibration Injections Under the Microscope

More from Chromatography Life All episodes →

1. 

   S2 · E1 · 18 Mar 2026 · 26 min

   Analytics That Matter in Biosimilar Development

   In this episode of Chromatography Life, Neil Lander and Colette Quinn, Sr. Director of Light Scattering in QC at Waters Corporation break down how the October 2025 FDA draft guidance is reshaping expectations for biosimilar development. They explore why LC and orthogonal techniques like MALS are becoming essential for demonstrating analytical similarity and reducing reliance on clinical studies. Colette also highlights how tools like Empower™ Software support data integrity, reproducibility, and faster development timelines.

2. 

   S1 · E12 · 10 Dec 2025 · 23 min

   Celebrating a year of Chromatography Life Podcast

   In this special Year in Review episode of Chromatography Life , host Neil Lander reflects on a year of engaging conversations with both Waters colleagues and customers from across the analytical science community. Neil shares what made each episode memorable, from deep technical insights to the personal stories behind the science.

3. 

   S1 · E11 · 12 Nov 2025 · 41 min

   Peak Integration in Chromatography – Practical Tips for Smarter Analysis

   In this episode, Neil Lander sits down with renowned analytical chemist Bob McDowall to explore the complexities of chromatographic peak integration. With over 50 years of experience, Bob shares insights into data integrity, regulatory compliance, and the evolving role of manual vs. automated integration. The conversation dives into real-world examples, AI's potential role in chromatography, and best practices for developing scientifically sound SOPs.

4. 

   S1 · E10 · 7 Oct 2025 · 39 min

   Rediscovering Slalom Chromatography – A Forgotten Technique Reimagined

   In our latest episode of Chromatography Life podcast, we explore a fascinating and nearly forgotten separation technique—slalom chromatography—with Dr. Fabrice Gritti, Consulting Scientist at Waters Corporation. Dr. Gritti brings decades of expertise in separation science and shares how this 1980s-era method is being revived to meet today's challenges in DNA and RNA analysis. Dr. Gritti also shares his vision for the future of chromatography, including AI-driven column design and 3D-printed stationary phases.

5. 

   S1 · E9 · 9 Sep 2025 · 29 min

   Adopting AQbD Principles to Method Development

   In Episode 9 of Chromatography Life, we sit down with Richard Verseput, a pioneer in QbD-driven analytical development, to explore how automation, risk assessment, and smart experimental design are revolutionizing chromatography. From cutting-edge tools like Fusion QbD to real-world strategies for building robust, adaptable methods, this episode is packed with insights that can transform your lab's efficiency and precision. Whether you're optimizing LC-MS workflows or navigating regulatory expectations, this is a must-listen for every analytical scientist.

6. 

   S1 · E7 · 9 Jul 2025 · 11 min

   Tools to Support Enhanced Method Development

   Join host Neil Lander as he sits down with Margaret Maziarz, Principal Scientist at Waters Corporation, to discuss the latest tools and strategic approaches to optimizing method development. Margaret guides us through the advantages to various types of instrumentation, the importance of selecting the right column chemistry, and the powerful capabilities of Empower software. She highlights the critical role of monitoring method performance over time and the challenges of transferring methods between LC systems. For those looking for a quick dose of method development expertise, this episode…

7. 

   S1 · E6 · 19 Jun 2025 · 24 min

   Advancements and Challenges in GLP-1 Peptide Drugs

   This episode of Chromatography Life takes a closer look at the evolving landscape of synthetic peptide drugs - one of the most compelling frontiers in biopharmaceutical analysis. Joining us is Matt Lauber, Senior Director at Waters and a recognized authority in bioanalysis and drug product characterization, who shares both his personal and professional journey, along with his insights into the science shaping today's peptide therapeutics. We discuss the growing significance of GLP-1 peptide drugs, the analytical hurdles they present, and the chromatographic techniques that help ensure their…

8. 

   S1 · E5 · 12 May 2025 · 28 min

   Challenges of Chromatographic Analysis for New Modalities

   Join host Neil Lander on Chromatography Life as he interviews, Arnaud Delobel, R&D and Innovation Director at Quality Assistance. In this episode, Arnaud discusses chromatographic analysis for new modalities, with adeno-associated viruses (AAVs) in the spotlight. He discusses the complexities of analyzing these large biomolecules and the innovative techniques being developed to improve their characterization. Tune in to glimpse the future of chromatography and learn about the incredible advancements that are helping to tackle some of the toughest human health challenges.

9. 

   S1 · E4 · 13 Apr 2025 · 14 min

   Automating Dissolution in the Laboratory

   Join host Neil Lander on Chromatography Life as he interviews Ben Calvopina, Application Scientist and expert in dissolution testing at SOTAX. Ben shares his journey from service engineering to leading automation projects, highlighting the impact of automation on efficiency and accuracy in pharmaceutical quality control. The episode explores the practical aspects of automating dissolution methods and the importance of validation to ensure reliable results. Tune in to this episode to learn about the latest trends and future directions in chromatography and dissolution.

10. 

    S1 · E3 · 17 Mar 2025 · 14 min

    The Evolution of UPLC Columns

    In this episode of the Chromatography Life podcast, our host Neil Lander sits down with Tom Walter, a corporate fellow at Waters, to explore the fascinating journey of UPLC column evolution. Tom, a seasoned expert with numerous patents and innovations under his belt, shares his experiences and insights from his extensive career in chromatography. From the early days of large particle columns to the cutting-edge small particle technology of today, Tom discusses the challenges, breakthroughs, and environmental impacts of UPLC advancements. Join us for an engaging conversation that sheds light…