#215 Gallbladder & Biliary Testing: 5 Pearls Segment

More from Core IM | Internal Medicine Podcast All episodes →

1. 

   21 min

   #220 CRC Screening Nuances: 5 Pearls Segment Part 2

   “What’s the best way to screen?” This episode breaks down the pros, limitations, and follow-up needs of FIT, Cologuard, CT colonography, and colonoscopy to help you choose the right screening option for your patients. Also learn practical colonoscopy surveillance intervals based on polyp size, number, and pathology. 🔹 Sponsor: Search “ Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here! 🔹 Transcript and Show Notes 01:24 | Screening Options Besides Colonoscopy 11:22 | How FIT, FIT-DNA, and CT colonography differ and when each makes…

2. 

   34 min

   #219 Updates in Triglycerides

   “The triglycerides are high. Now what?” This episode breaks down a practical approach to elevated TGs, from knowing when to check ApoB or non-HDL-C to choosing lifestyle changes, lipid-lowering medications, and when to suspect an underlying genetic disorder. 🔹 Transcript and Show Notes 02:17 | Check a non-HDL-C or ApoB if TGs are ≥150 mg/dL 07:18 | Address waist circumference and lifestyle before meds for high TGs 10:52 | Dr. Watson’s 3-day carbohydrate responsiveness trial 17:07 | Order a fasting or nonfasting lipid panel? 19:00 | When do you reach for TG-lowering medications? 25:26 |…

3. 

   15 min

   #218 Early-Onset CRC: 5 Pearls Segment Part 1

   “Too young for colon cancer.” This episode unpacks the red flags of early-onset CRC, from blood in the stool and iron deficiency anemia to persistent abdominal pain and changes in bowel habits, and offers practical pearls for closing the clinical loop. Also learn why a “negative” family history may need a yearly refresh. 🔹 Sponsor: Search “ Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here! 🔹 Transcript and Show Notes 01:45 | Colorectal cancer rising in younger adults 06:42 | Why screening starts at age 45 08:15 | What may be driving…

4. 

   38 min

   #217 Treatment for Alcohol Use Disorder: 5 Pearls Segment

   “It didn’t work.” This episode breaks down practical treatment options (dosing options for naltrexone, acamprosate, topiramate, gabapentin) and counseling pearls to help you meet patients where they are and support their recovery. Also discover blind spots in detox and rehab centers. 🔹 Transcript and Show Notes 🔹 Explore ACP’s Substance Use Disorder Education Hub for videos and an AI-powered patient simulation to practice alcohol-use conversations: https://www.coreimpodcast.com/SUDhub Alcohol Use and Chronic Health Conditions Mini Video Series 01:55 | #1: Naltrexone 12:06 | #2 Acamprosate…

5. 

   40 min

   #216 Clinician Grief: At the Beside Segment

   Have you ever lost a patient and found yourself thinking about them long after the shift ended? This episode explores the grief clinicians can carry after a patient dies, including the losses that aren’t always obvious. We also discuss ways to work through that grief, recognize when it becomes complicated, and lean on your team for support . 🔹 Transcript and Shownotes 04:12 | What is Clinician Grief? 10:02 | Types of Losses 10:22 | Loss of a close relationship with a particular patient 12:56 | Loss due to a professional's identification with the pain of family members 13:56 | Loss of one's…

6. 

   45 min

   #214 Hyponatremia Management: A Core IM Classic

   Throwback: Should you really fluid-restrict every patient with SIADH? When can IV fluids make hyponatremia better or worse? Are salt tabs actually doing enough? And what can urine studies tell you before you start treatment? Join us for a practical, physiology-driven approach to hyponatremia management, from fluids and solutes to loop diuretics and identifying the underlying cause. 🔹 Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here . 🔹 Transcript and Shownotes 6:46 | Pearl 1: Key Principles 15:13 | Pearl 2: Fluids…

7. 

   33 min

   #213 Hypertension First-Line Medications Troubleshooting | Bread & Butter Series

   Why can lower-dose combinations be more effective and better tolerated than maximizing one medication? How to troubleshoot common challenges such as amlodipine edema, gout, electrolyte abnormalities, and the patient who says they cannot tolerate anything? Why ACT ( ARBs, Calcium Channel Blockers, Thiazides ) is the preferred first-line framework, and how to personalize medication choices based on comorbidities and side effects. 🔹 Sponsor: Oakstone CME Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP 🔹 Transcript and Shownotes 03:00 | Diagnosing Hypertension 04:10 | When…

8. 

   24 min

   #212 Top 10 Highlights of the New Lipid Guidelines

   Learn from primary care docs what has been practiced and changed from the 2026 ACC/AHA Lipid Guidelines! Learn how the new CPR framework (Calculate, Personalize, Reclassify) and PREVENT risk calculator change statin decisions, why LDL targets are back , and when to use Lp(a), ApoB, and coronary artery calcium (CAC) testing. Discover updated risk-enhancing factors, expanded indications for non-statin therapies, and practical strategies to personalize lipid management for both primary and secondary 🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery…

9. 

   34 min

   #211 Breaking Down MASLD vs. MASH and the MAESTRO-NASH & ESSENCE Trials: Beyond Journal Club Segment

   MASLD affects nearly one in three adults worldwide, yet many patients remain undiagnosed until advanced fibrosis or cirrhosis develops. So, which patients should clinicians actually be screening? When is a FIB-4 enough, and when should we move to elastography or hepatology referral? And are we finally entering an era where we can meaningfully treat MASH? In this Beyond Journal Club episode, we unpack the evolving language of steatotic liver disease and take a close look at two major trials: MAESTRO-NASH studying resmetirom, the first FDA-approved liver-directed therapy for MASH, and ESSENCE,…

10. 

    26 min

    #210 HTN in Dialysis: 5 Pearls Segment

    What blood pressure should we target in patients on hemodialysis? Why volume control remains the foundation of treatment? How blood pressure targets differ from the general population. Learn practical pearls on medication timing around dialysis, drug dialyzability , antihypertensive selection, and strategies to prevent intradialytic complications while optimizing long-term outcomes. 🔹 Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here . 🔹 Transcript and Shownotes: 02: 19 | Pearl 1: Blood Pressure Targets 09: 40 |…