Podcast · Tech & Science

Demystifying Genetics

by Matt Burgess · English · Tech & Science

This is a podcast series called Demystifying Genetics where I, Dr Matt Burgess, Genetic Counsellor interview other genetic counsellors, people working in genetics or people affected by genetic conditions. We chat about human clinical genetics, genetic counselling, ethics, pyschosocial issues and mor

New episodes: Weekly
Typical length: 50 min
Latest: 15 Dec 2025
Language: English

Latest episode

15 Dec 2025 · 54 min

Becoming a Genetic Counselor: Identity, Mentorship, and Belonging. Demystifying Genetics with Rachel Mills.

Host Matt Burgess talks with Dr. Rachel Mills, a genetic counsellor and educator, about her PhD work on professional identity, how conferences and mentorship shape early-career genetic counsellors, and the changing roles of teaching, research and advocacy in the field. The conversation covers training choices, the role of research and mindfulness in education, challenges in recruitment for studies, and practical advice for building community and confidence as genetic counsellors.

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Earlier episodes 29 most recent

E29 · 8 Dec 2025 · 45 min
From Navy Decks to Genetic Docs: One Man’s AFAP Journey. Demystifying Genetics with Dan Shockley (Favourite gene: APC).
Host Matt Burgess speaks with Navy veteran Dan "Dry Dock" Shockley, who was diagnosed at 51 with attenuated familial adenomatous polyposis after routine screening revealed hundreds of polyps. Dan shares his experience with genetic testing, major surgeries including a permanent ileostomy and pancreatic-sparing resection, and how he connected with Dr. Henry T. Lynch. Now an advocate and educator, Dan discusses surveillance, genetic counselling, living positively with rare gene mutations, and his work teaching medical students and health professionals worldwide about early detection and…
E28 · 1 Dec 2025 · 48 min
From Values to Gene Therapy: Leading the Future of Genetic Counselling. Demystifying Genetics with Sara Pirzadeh - Miller. (Favourite gene: CDH1)
Host Matt Burgess speaks with genetic counsellor and NSGC president Sara Pirzadeh‑Miller about her early research on values in genetic counselling, how life experience shapes practice, and the evolving role of genetic counsellors. They also discuss the clinical challenges of the CDH1 gene, risk interpretation, screening versus prophylactic surgery, the rise of genetic counselling assistants, and future genomic innovations such as gene therapies and improved risk stratification.
E27 · 24 Nov 2025 · 50 min
Genetic Counsellors Take the Lead: From Mackenzie’s Mission to National Genomics. Demystifying Genetics with Kirsten Boggs
Senior genetic counsellor Kirsten Boggs discusses building GCR Connect, the rise of genetic counsellor-led research, and lessons from Mackenzie’s Mission - Australia’s national reproductive carrier screening study. We explore practical challenges and ethics of large-scale genomic screening, the future of newborn whole-genome programs, consent and data storage issues, and how genetic counsellors can bridge clinical care, research and policy.
E26 · 17 Nov 2025 · 54 min
PGT Unpacked: Ethics, Linkage and Hard Choices in Reproductive Genetics. Demystifying Genetics with Erica Pai
In this episode host Matt Burgess speaks with Canadian genetic counsellor Erica Pai about pre‑implantation genetic testing (PGT). They discuss how PGT has evolved, technical and ethical challenges (including difficult genes like CYP21A2), the continuing role of linkage analysis in embryo testing, and the complexities of mosaic and segmental results. They also cover the emotional and practical aspects of counselling families through IVF and PGT, issues of access and equity, and the importance of clinical support when deciding whether to pursue testing.
E25 · 10 Nov 2025 · 57 min
When Genes Meet Justice: Kidney Risk, Gene Therapy, and Community Care. Demystifying Genetics with Barbara Harrison
Host Matt Burgess speaks with Assistant Professor Barbara Harrison of Howard University about APOL1-related kidney disease, sickle cell disease, and the role of cultural awareness in genetic counselling.They discuss health inequities, community trust around new therapies like gene editing, and efforts to increase diversity in the profession through the GOLDEN mentorship program.
E24 · 3 Nov 2025 · 46 min
When Genes Guide Care: BRCA, Rapid Testing and Real Choices. Demystifying Genetics with Mary-Anne Young (Favourite Genes BRCA1&2).
Dr Matt Burgess talks with Mary-Anne Young about the real-world impact of genomics on healthcare and genetic counselling. They cover BRCA1/2 history, rapid testing, integration with oncology, and using polygenic risk to personalise care.The episode explores family systems and counselling techniques, ethical issues around returning research findings, workforce diversity, and practical steps to implement genomic advances in clinics.Listeners will get a concise look at how genomics is changing patient care, communication with families, and the direction of the genetic counselling profession.
E23 · 27 Oct 2025 · 45 min
When Genes Meet Heart: Inside Cardiac Genomics. Demystifying Genetics with Jodie Ingles (Favourite Gene: MYH7)
Host Matt Burgess talks with Dr Jodie Ingles, a leading cardiac genetic counsellor and researcher, about inherited heart conditions, supporting families after sudden cardiac events, and translating genomic discoveries into clinical care. The episode covers variant classification, health equity, the evolving role of genetic counsellors, and the importance of mentorship and practical changes needed to bring genomic testing into everyday practice.
E22 · 20 Oct 2025 · 44 min
Huntington’s Unlocked: Ethics, Exclusion Testing & New Gene Therapies. Demystifying Genetics with Sandra Peacock (Favourite Gene: HTT).
Genetic counsellors Matt and Sandra explore Huntington disease, prenatal and lab-based testing ethics, and how lab genetic counsellors act as gatekeepers. They discuss exclusion testing, the challenges of writing clear lab reports, and recent advances in gene therapy.The episode also covers the growing role of AI and automation in genetic labs, the evolving responsibilities of lab GCs, and how testing impacts life choices like career planning and family decisions.
E21 · 13 Oct 2025 · 48 min
From Mistake to Mastery: A Genetic Counsellor’s Story. Demystifying Genetics with Rachel Vanneste (Favourite gene SHH)
Host Matt Burgess talks with Canadian genetic counsellor Rachel Vanneste about lessons learned from early-career mistakes, the unexpected charm of the sonic hedgehog gene (SHH), and how sales and business skills are shaping modern genetic counselling. They discuss counselling in a second language, career pivots across clinic, industry and labs, the case for embedding genetic counselling in primary care, and the importance of volunteering in the profession.
E20 · 6 Oct 2025 · 48 min
Telehealth, Mainstreaming & the Modern Counsellor. Demystifying Genetics with Dawn Allain. (Favourite gene - GNAS)
Host Matt Burgess speaks with Dawn Allain, a genetic counsellor and leader at Ohio State University, about how genetic counselling has evolved. They discuss telehealth, mainstreaming of genetic testing, and how education and competency-based training must adapt for today’s genomic era. The episode also covers leadership and mentorship in the profession, specialty practice areas like imprinting disorders, and emerging topics such as pharmacogenomics and epigenetics — highlighting where the field has been and where it’s going.
S5 · E9 · 29 Sep 2025 · 50 min
Reinventing Clinical Trials: How Sano Genetics Puts Patients First
Host Matt speaks with Dr. Patrick Short, scientist and CEO of Sano Genetics, about building a patient-centered genomics company, the challenges of designing and recruiting for clinical trials, and the evolving role of diagnostics in precision medicine. They discuss Short’s research into non-coding DNA, the practical and ethical questions around predictive and newborn screening, gene therapy prospects, and lessons from his personal family experiences that shape the company’s patient-first approach.
S5 · E8 · 22 Sep 2025 · 45 min
Hidden Codes: Hereditary Melanoma, CDKN2A and the Families Behind the Genes
Dr. Aideen McInerney-Leo explores hereditary melanoma (CDKN2A), diagnostic disclosure in Turner syndrome, mainstreaming genomics, gene therapy, and the expanding role of genetic counsellors in research and patient care. Through clinical stories, family perspectives and practical takeaways on testing and screening, this episode highlights how research and clear communication improve outcomes — with a personal note on the therapeutic craft of bead-making.
S5 · E7 · 15 Sep 2025 · 57 min
Who Is a Genetic Counsellor? Redefining Identity in Genomics
Host Matt chats with American genetic counsellor Dr Lisa Schwartz about the evolving professional identity of genetic counsellors, the role of networking and qualitative research (including authors' positionality), and how clinical training translates into lab, policy and education roles. They also swap stories about travel, outdoor winery concerts, Stevie Nicks, their dogs, and advances in genetics such as Duchenne research, while discussing how training and definitions may need to change as the profession grows.
E19 · 8 Sep 2025 · 40 min
Jewish Ancestry & Genetics: Carrier Screening, Community and Choice
Host Matt Burgess interviews Gidon Schwartz from Jnetics, a UK charity offering pre-conception carrier screening and partnering with the NHS to increase access to BRCA and carrier testing for people with Jewish ancestry. They discuss why ancestry matters for certain recessive conditions, how testing and outreach have evolved, ethical and identity challenges around asking about ethnicity, and where to find resources and genetic counseling.
E18 · 1 Sep 2025 · 59 min
From Clinic to TikTok: Dena DNA’s Journey Demystifying Genetics
Host Matt Burgess interviews genetic counsellor and content creator Dena Goldberg (Dena DNA) about her path from clinical genetics to social media, her work educating the public on Lynch syndrome and cancer genetics, and how storytelling makes complex science accessible. The episode also covers Dena’s personal experiences with infertility and an undiagnosed medical condition, her tips for self-advocacy in healthcare, and how authentic content can empower patients and combat misinformation.
S5 · E4 · 25 Aug 2025 · 28 min
Living with CMT: Finding Answers in the SORD Gene
In this episode Matt Burgess interviews Darryl Beitsch about his lifelong experience with Charcot‑Marie‑Tooth (CMT) and the late discovery that his neuropathy is caused by mutations in the SORD gene. They discuss diagnosis, nerve testing, genetic testing advances, family implications, volunteering with CMT Australia, and the importance of research, community support, and practical management.
S5 · E3 · 18 Aug 2025 · 1 hr 4 min
‘Powerhouse’ Lives: A Genetic Counselor’s Journey Through Mitochondrial Disease (GUK1)
Genetic counsellor Matt talks with Devin Shuman, a fellow genetic counsellor and rare-disease patient, about her family’s diagnosis of mitochondrial DNA depletion syndrome, the long diagnostic odyssey from muscle biopsy to a candidate gene discovery, and the realities of genetic testing. Devin discusses the process of a disease causing variant in GUK1 being identified. They also explore how mito affects day-to-day life, the promise and limits of experimental treatments and compassionate access, the strength of the rare-disease community, and the small joys—service dogs, activism, and…
S5 · E2 · 12 Aug 2025 · 26 min
Unraveling Charcot-Marie-Tooth (CMT): A Journey Through Generations. Demystifying Genetics and CMT1A with Peter Critchley
Welcome to another enlightening episode of Demystifying Genetics, hosted by Matt Burgess. In this episode, we dive deep into the world of Charcot-Marie-Tooth disease (CMT) with Dr. Peter Critchley, who himself is affected by this genetic condition. The conversation uncovers the nuances of CMT, focusing on CMT1A - the specific gene in Peter's family. Peter shares insights into how this hereditary peripheral neuropathy affects various aspects of life, from physical challenges to societal misconceptions. The episode sheds light on his personal experiences, from childhood nerve conduction tests…
S5 · E1 · 14 Jul 2025 · 53 min
Genetic Ventures: From Counseling to Entrepreneurship. Demystifying genetics with Erica Ramos (Favourite gene - HFE Hereditary Hemochromatosis)
Join host Matt as he engages in a captivating conversation with his guest, American genetic counselor Erica Ramos. In this episode of Demystifying Genetics, Erica shares insights into her favorite gene, the HFE gene, associated with hereditary hemochromatosis. Their discussion delves into the evolution of understanding this condition and the importance of prevention and proactive health measures. The episode also explores the diverse roles of genetic counselors beyond clinical settings and Erica’s journey, encompassing her experiences in direct-to-consumer testing and the startup world. Tune…
S4 · E17 · 2 Jun 2025 · 53 min
From Rural Roots to Genetic Advocate. Demystifying Genetics with Kate Wilson.
In the season finale of Demystifying Genetics, host Matt is joined by fellow genetic counselor and podcaster, Kate Wilson, the voice behind All Access DNA. They delve into the evolving landscape of genetic counseling, exploring Kate's personal journey from rural beginnings to becoming a passionate advocate for equitable access to clinical genetics. This episode highlights the disparities within healthcare systems, the importance of accessible genetic information, and how Kate is breaking norms with her dual role as a counselor and a science communicator. Tune in for a compelling discussion…
S4 · E16 · 26 May 2025 · 54 min
Inside Genetic Counselling: Navigating Direct-to-Consumer Testing and Research. Demystifying Genetics with Joshua Nolan
In this episode of "Demystifying Genetics," host Matt Burgess speaks with English research genetic counsellor Joshua Nolan. They explore topics such as the underrepresentation of males in genetic counselling, the intricacies of direct-to-consumer genetic testing, and the symbiosis between clinical and research work in genetics. Joshua shares his insights into the professional challenges and personal experiences that shape his approach to genetic counseling. They also discuss the importance of emotional intelligence in the field and how genetic counselors play a crucial role in bridging the…
S4 · E15 · 20 May 2025 · 41 min
Pioneering Genetics in Ghana: A Groundbreaking Journey. Demystifying Genetics with Ahmed-Sherrif Kanvela Yussif
This episode of the "Demystifying Genetics" podcast features an insightful conversation with Ahmed-Sherrif Kanvela Yussif, one of the first genetic counsellors in Ghana. Host Matt Burgess delves into Ahmed's pioneering journey, exploring the role of genetic counseling in Ghana's healthcare system and its impact on public health, particularly regarding sickle cell disease. Ahmed shares his inspiring transition from teaching to genetic counseling and discusses the cultural and religious dynamics influencing healthcare decisions in West Africa. Despite connectivity challenges, this episode…
S4 · E14 · 12 May 2025 · 53 min
Genetic Counseling Unwrapped: A Deep Dive. Demystifying Genetics with Jaime Jessen-Brown
Join host Matt, a seasoned genetic counselor, as he delves into the evolving world of clinical genetics in the latest episode of Demystifying Genetics. With guest Jaime Jessen-Brown, a genetic counselor based in Toronto, Canada, this podcast episode explores their shared journey from studying in Newcastle, Australia, to Jaime's diverse career path. Jaime shares insights from her experience transitioning from a prenatal clinic to a Medical Science Liaison role, discussing the challenges and advancements in somatic genetic testing and the integration of genetics into oncology. They reflect on…
S4 · E13 · 5 May 2025 · 46 min
Unraveling Polygenic Risk Scores (PRS) in Genetics. Demystifying Genetics with Kylie Morgan
Join Matt Burgess in this episode of Demystifying Genetics as he sits down with Dr. Kylie Morgan, a genetic counsellor from Melbourne, to explore the emerging field of polygenic risk scores. Discover how this new form of genetic testing is shaping clinical practices in both Australia and the United States. Learn about the personal experiences of genetic counsellors, Matt and Kylie, as they discuss the intricacies of genetic testing and the evolving landscape of genetic counseling. They share anecdotes about their own dogs' quarantine experiences, drawing parallels to their professional…
S4 · E12 · 21 Apr 2025 · 1 hr 1 min
How Genetic Counseling Is Evolving Beyond Hospital Walls. Demystifying Genetics with Lauren Giannetti Sferrazza
Lauren Giannetti-Sferrazza, a genetic counselor from New Jersey, shares her journey transitioning from clinical practice to industry and discusses the evolution of genetic counseling roles. Throughout the conversation, she offers insights into balancing professional responsibilities and personal experience as a pregnant genetic counselor preparing for childbirth.• Clinical burnout as a catalyst for moving to industry positions• Shifting perceptions of industry roles from "the dark side" to valuable career paths• Potential for broader patient impact through industry versus direct clinical…
S4 · E11 · 14 Apr 2025 · 44 min
Beyond Genes: Can We Truly Measure the Impact of Genetic Counselling? Demystifying Genetics with Marion McAllister
Professor Marion McAllister shares the fascinating journey of developing the Genetic Counselling Outcome Scale, a groundbreaking tool that measures patient empowerment rather than just anxiety reduction. We explore how this simple questionnaire transformed genetic counselling assessment worldwide and evolved to meet changing healthcare needs. • Creating the first standardised measure for genetic counselling outcomes based on patient-reported benefits • Translating the scale ac...
S4 · E10 · 8 Apr 2025 · 48 min
What Happens When You Become Your Own Boss in Genetic Counseling? Demystifying Genetics with Scott Weissman.
Scott Weissman shares his journey of building a telehealth genetic counseling private practice, discussing the challenges of insurance contracts, licensing across states, and adapting to technological changes in cancer genetics. • Opened private practice in 2016 as a side business, now seeing 15-20 patients weekly • Despite having licenses in 25-26 states, establishing insurance contracts remains a major obstacle • Pivoted to 100% telehealth during the pandemic, offering after...
S4 · E9 · 1 Apr 2025 · 55 min
Resilience After Redundancy: A Genetic Counsellor’s Journey; Demystifying Genetics with Angela Arnold Ross
Matt sits down with Angela Arnold-Ross, an Australian genetic counsellor living in New Jersey, for a candid and heartfelt conversation about professional resilience and personal growth in the field of genetic counselling. • Sharing the experience of being laid off after 15 years and the emotional impact of unexpected job loss • The stages of grief following a career disruption and how writing became therapeutic • Using networking to rebuild a career path through connections wi...
S4 · E8 · 24 Mar 2025 · 58 min
Inherited Hearts and Healing Minds: A Cardiac GC’s Journey. Demystifying Genetics with Laura Yeates
Send us a text Dr. Laura Yeates shares her journey as a cardiac genetic counsellor specialising in inherited heart diseases and supporting families affected by sudden cardiac death. We explore her recent PhD research on developing support interventions for these families and discuss the importance of wellbeing for genetic counselling professionals. • Cardiac genetic counselling focuses on inherited cardiomyopathies and arrhythmias • Dr. Yeates completed her PhD during COVID, developing suppo...

About Demystifying Genetics

Demystifying Genetics is a English tech & science podcast from Matt Burgess. Melo plays each episode straight from the publisher's own feed — no ads added, no account needed — and remembers where you stopped, in this browser only.

Publisher: Matt Burgess
Language: English
Category: Tech & Science
New episodes: Weekly
Typical length: 50 min
Latest episode: 15 Dec 2025
Feed: RSS — paste into any podcast app
Apple Podcasts: podcasts.apple.com/podcast/id1811941726

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