Video Is About to Stop Being One-Way (and That Changes Everything) | Victor Riparbelli, Synthesia

More from Eye On A.I. All episodes →

1. 

   E372 · 13 Aug 2026 · 59 min

   American Companies Have 36 Months to Go AI-Native or Get Left Behind | Drew Cukor, TWG AI

   The same tools that slowed the U.S. military down in Afghanistan (PowerPoint, Excel, email, and Word) are now slowing American businesses down in the AI race. Drew Cukor spent 30 years as a Marine intelligence officer, helped build Project Maven into a battlefield command and control system, served as Chief Data Officer at JP Morgan, and is now leading AI transformation at TWG AI. In this episode, he joins Craig Smith to make a case that most enterprise AI strategies are fundamentally broken, not because the technology isn't there, but because companies are storing their data in Microsoft…

2. 

   E371 · 10 Aug 2026 · 59 min

   In 5 Years, 90% of What You Use AI For Will Run on Your Smartphone | Paolo Ardoino, Tether

   Hundreds of billions of dollars are flowing into AI data centers right now, and Paolo Ardoino, CEO of Tether - the company behind the world's most widely used stablecoin with 573 million users - thinks that investment is going to age very badly. In this episode, he joins Craig Smith to explain QVAC, Tether's open-source platform for running AI on smartphones, laptops, and edge devices, and to make a case that within five years, 90% of what ordinary people use AI for will run entirely on consumer hardware, without touching a data center. The evidence is already there: Tether's team built a…

3. 

   E370 · 3 Aug 2026 · 59 min

   AI Agents Fixing Your IT Before You Even Know Something Broke | Erhan Giral & Ryan Manning, BMC Helix

   Most enterprise IT teams spend the majority of their time fighting the same fires repeatedly. BMC Helix is building the AI system that handles those fires automatically, detecting anomalies, tracing root cause through millions of asset relationships, generating remediation plans, and learning from every incident it resolves. Craig Smith sits down with Erhan Giral, VP of AI Strategy and Innovation at BMC Helix, and Ryan Manning, Chief Product Officer at BMC Helix, to explain how agentic AI is transforming IT service management from a reactive, human-driven process into something closer to a…

4. 

   E369 · 30 Jul 2026 · 1 hr 6 min

   Real AI Transformation Costs HALF of Everyone's Salary for 2 Years | Chris Blackburn, Liatrio

   Most companies think they're transforming with AI. They're not, and the gap between what they believe and what's actually happening on the ground is costing them far more than they realize. In this episode, Craig Smith sits down with Chris Blackburn, founder and CEO of Liatrio, a consultancy that has spent a decade embedding directly inside large enterprises to help them actually change how they work, not just what tools they use. The conversation opens with a striking data point: the average enterprise Blackburn works with operates at just 5 to 6% efficiency, meaning employees spend only…

5. 

   E368 · 29 Jul 2026 · 46 min

   "According to NASA's Definition of Life, I'm Not Alive" - Why Nobody Can Define Life | Dr. Kate Adamala

   Nobody has ever built a cell from scratch - assembled entirely from purified molecules on a shelf - that can feed itself, grow, and split into daughter cells through its own genetic activity. Until now. Dr. Kate Adamala, a synthetic biologist and a professor of genetics at the University of Minnesota, whose lab just published a landmark paper on what she calls "spud cells," joins Craig Smith to explain what her team built, why it matters, and what it will take to go from proof of concept to a platform that could eventually replace every molecule civilization currently extracts from…

6. 

   E366 · 15 Jul 2026 · 45 min

   6 in 10 Enterprises Can't Find the Root Cause When Their AI Workloads Fail | Paul Appleby, Virtana

   Companies are spending billions building AI factories, but most of them can't tell you why their AI workloads are failing, whether their GPUs are actually being used, or what their infrastructure is going to cost them when agents start running at scale. Paul Appleby, CEO of Virtana, joins Craig Smith to discuss the findings of their AI Factory Reality Check study, a research report that reveals a striking and underappreciated gap between the pace of AI infrastructure investment and the governance needed to run it safely and efficiently. Six in ten enterprises, the study found, cannot…

7. 

   E365 · 13 Jul 2026 · 56 min

   Inside the Enterprise Browser Rebuilding Security for the AI Era | Bradon Rogers, Island

   AI is moving faster than enterprise security systems were designed to handle. In this episode of Eye on A.I., Craig Smith speaks with Bradon Rogers, Chief Customer Officer at Island, Island about how companies are struggling to govern the rise of AI agents, browser-based workflows, and unsanctioned AI tools inside the workplace. The conversation explores why traditional "block-and-control" security models are breaking down and how a new approach, embedding policy directly into the browser and user workflows, may offer a path forward. It also dives into emerging risks like prompt injection…

8. 

   E364 · 10 Jul 2026 · 23 min

   What Industrial AI Actually Looks Like | Kriti Sharma, Nexus Black

   Most AI is built for people sitting at desks. Kriti Sharma builds it for the people who work in refineries, aircraft hangars, and utility networks responding to wildfires at 4 a.m. and she spends weekends on-site with them to make sure what she builds actually holds up. In this episode, Kriti joins Craig Smith to discuss what industrial AI really looks like when failure genuinely isn't an option, and why the gap between an impressive AI pilot and a production-grade AI system is so much wider in the physical world than most technology companies appreciate. The conversation is grounded in…

9. 

   E363 · 7 Jul 2026 · 48 min

   The Biggest AI Security Problem Isn't the Model. It's This. | Devvret Rishi

   What is an AI agent, really? Strip away the hype, and it's a model with access - to tools, APIs, databases, email, anything that lets it take real action instead of just generating text. That access is exactly where the risk lives, and Devvret Rishi, GM of AI at Rubrik, and former co-founder & CEO of Predibase, joins Craig Smith with a string of real-world incidents that make the case concrete: AWS reporting four major outages in 90 days after deploying coding agents, a Meta-related agent that deleted someone's emails while they were actively asking it to stop, and Rubrik's own internal…

10. 

    E362 · 5 Jul 2026 · 50 min

    Big Pharma Fails 50% of the Time in Phase Three. AI Can Fix That | Vin Singh, BullFrog AI

    It costs up to $2 billion and fifteen years to develop a drug, and big pharma still fails half the time at the final stage. BullFrog AI founder, Chairman, and CEO Vin Singh joins Craig Smith with a clear diagnosis of why: the industry keeps picking the wrong drug target from the beginning, and no amount of downstream optimization fixes a fundamentally wrong starting point. Built on AI technology originally developed at Johns Hopkins' Applied Physics Lab, BullFrog has assembled a three-stage platform that cleans messy clinical data, runs causal analysis to map disease pathways, and then ranks…