Podcast · Tech & Science

JHLT: The Podcast

The Journal of Heart and Lung Transplantation podcast airs each month and features the JHLT Digital Media Editors in round table talks with the Journal's contributors.

New episodes: Every two weeks
Typical length: 14 min
Latest: 7 Oct 2026
Language: English

Latest episode

7 Oct 2026 · 33 min

Episode 93: ISHLT Consensus Document: BLAD Definition, Timing, Outcomes

Today, JHLT: The Podcast discusses the recent ISHLT consensus document " Baseline Lung Allograft Dysfunction: Definition, Timing, and Implications for Outcomes—An ISHLT Consensus Document ." Now available online at JHLT —and a helpful companion perspective piece from the authors appears in the print October issue of JHLT . Today's guests are co-leads on the document, Jens Gottlieb, MD , of Hannover Medical School and Kieran Halloran, MD, MSc , of the University of Alberta. They discuss: Why rapid increases in usage of "BLAD" in the literature meant it was time for a formal definition Major…

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Earlier episodes 29 most recent

S6 · E18 · 16 Sep 2026 · 17 min
Episode 92: Treating PPAS with Stent-Based Pulmonary Angioplasty
In this episode, JHLT: The Podcast continues the Pulmonary Hypertension theme for the month, exploring the study " Long-Term outcomes of stent-based pulmonary angioplasty for isolated peripheral pulmonary artery stenosis ," which appears in the September print issue of JHLT . Today's guest is author Hiroto Shimokawahara, MD , of the Okayama Medical Center in Japan. Dr. Shimokawahara's discussion with Digital Media Editor Van-Khue Ton covers: What the study contributes to the clinical literature with longer-term outcomes of stent-based pulmonary angioplasty in peripheral pulmonary artery…
S6 · E17 · 2 Sep 2026 · 13 min
Episode 91: Medical Therapy Pre- and Post-Pulmonary Endarterectomy
Today, JHLT: The Podcast discusses " Long-term effects of medical therapy pre- and post-pulmonary endarterectomy—insights from the UK CURATE registry ," a manuscript available online now and in the September print issue of JHLT . Today's guest is first author Paula Appenzeller, MD , of the National Pulmonary Vascular Diseases Unit at Royal Papworth Hospital in Cambridge. In the episode, Dr. Appenzeller and the editors discuss: How findings from the UK CURATE registry challenge assumptions about pre-operative therapy in CTEPH What's important about the 6-minute walk distance test How…
S6 · E16 · 19 Aug 2026 · 12 min
Episode 90: The ASSIST CLAD Study: Using Mesenchymal Stromal Cells in New-Onset CLAD
In this episode, JHLT: The Podcast explores the study " The ASSIST CLAD study: A phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunction ," which appears in the August print issue of JHLT . Today's guest is Daniel C. Chambers, MBBS, MD , of The Prince Charles Hospital and Queensland Lung Transplant Service in Brisbane, Australia. From across the dateline, he and Digital Media Editor Erika Lease discuss: What inspired the team to explore the use of mesenchymal stromal cell (MSC) infusions in CLAD patients Preparation and treatment…
S6 · E15 · 5 Aug 2026 · 15 min
Episode 89: Improved Outcomes and Utilization in Hearts With 10° Static Cold Storage
Today, JHLT: The Podcast discusses " Improved outcomes and donor utilization in heart transplantation with 10 °C static cold storage ," a manuscript available online now and in the August print issue of JHLT . Today's guest is senior author John Trahanas, MD , of the Vanderbilt University School of Medicine in Nashville, TN USA. In the episode, Dr. Trahanas and the editors discuss: What was learned from the lung 10°C trials and how the team adapted the devices for hearts The improved outcomes in PGD and survivability observed in the 10°C group How to determine if switching from ice to 10°C…
S6 · E14 · 15 Jul 2026 · 13 min
Episode 88: Looking Back: Is Sotatercept Safe in Patients with PAH?
In case you missed it, JHLT: The Podcast is re-releasing a past audience favorite for your listening pleasure. This month, we revisit a conversation regarding a study from the April 2025 issue of JHLT about the efficacy and safety of sotatercept in patients with PAH . This conversation with Ioana Preston, MD , of the Tufts University School of Medicine in Boston, explores: What makes sotatercept unique as the first "biologic" in the treatment of PAH Hypotheses about the mechanism of action in sotatercept Sotatercept's interaction with mPAP and what it indicates about the drug's action on the…
S6 · E13 · 1 Jul 2026 · 18 min
Episode 87: The Trifecta Heart Study: Assessing Donor Specific Antibodies in AMR
JHLT: The Podcast returns for July with a paper entitled " Comparing DSA-negative and DSA-positive antibody-mediated rejection in heart transplants: Results from the Trifecta-Heart study ," available online now and in the July print issue of JHLT . Today's guests are first author Katelynn S. Madill-Thomsen, PhD and senior author Philip F. Halloran, MD, PhD , both from the Alberta Transplant Applied Genomics Center in Canada. In the episode, the authors and editors discuss: Striking similarities—and key differences—in the DSA-negative and DSA-positive groups Changes to clinical practice based…
S6 · E12 · 17 Jun 2026 · 12 min
Episode 86: A Patient Perspective on Ghost Coverage and Access to Immunosuppressants
For the first time, JHLT: The Podcast welcomes a patient onto the podcast. The Digital Media Editors are pleased to welcome heart transplant recipient and patient advocate Payton Herres for a discussion about her recent perspective piece in JHLT . In this compelling, moving discussion, Payton shares: Her treatment story—from her congenital diagnoses to her life-changing transplant—and her donor's story The difference between coverage and access—and how FDA labeling affected her access to an important component of her care What she wishes clinicians understood about long-term care of…
S6 · E11 · 3 Jun 2026 · 13 min
Episode 85: Assessing SCAI Shock Classification in Post-Cardiotomy Patients
On JHLT: The Podcast , we kick off June with a paper entitled " Serial assessment of modified Society for Cardiovascular Angiography and Interventions SHOCK classification in post-cardiotomy patients ," which is available online now and in the June issue of JHLT . Today's guests are first author Ufuk Baldan, MD and senior author Patrick Klein, MD, PhD , both of the Amsterdam University Medical Center in the Netherlands. We discuss: The heterogeneous nature of post-cardiotomy shock and challenges to treat Should serial assessments become standardized post-cardiac surgery? Does SCAI staging…
S6 · E10 · 20 May 2026 · 7 min
Episode 84: What Was Hot at ISHLT2026
On this special episode of JHLT: The Podcast , the Digital Media Editors take a look back at the exciting science that was on display at ISHLT2026, the ISHLT 46 th Annual Meeting & Scientific Sessions. Topics include: Artificial intelligence and machine learning in transplantation, especially in assessing donor lungs and EVLP Cardiogenic Shock science at ISHLT2026, including a well-attended, all-new Academy The re-launch of the ISHLT International Thoracic Organ Transplant Registry, and the recent report in JHLT For the latest studies from JHLT , visit www.jhltonline.org/current , or, if…
S6 · E9 · 6 May 2026 · 14 min
Episode 83: Consensus on Graft Dysfunction within 72 Hours After Heart Transplant
JHLT: The Podcast starts May with an important ten-year update to a keystone document—the " ISHLT Consensus Conference on Graft Dysfunction within the First 72 Hours after Heart Transplantation ." The consensus summary—and a perspective piece by the authors —appears in the May issue of JHLT, and is available in full on ISHLT.org . The podcast is happy to host conference leader and first author Jon Kobashigawa, MD , Cedars-Sinai in Los Angeles, to talk about the consensus document, the conference, and PGD. The conversation includes discussion of: Why the document needed updating and how…
S6 · E8 · 30 Apr 2026 · 15 min
Episode 82: JHLT Special Issue: Device Therapies
In this episode, JHLT: The Podcast highlights a special issue of the Journal of Heart and Lung Transplantation that's just been released. The issue focuses on innovations in Device Therapies, and was edited by JHLT Deputy Editor Manreet Kanwar, MD, FACC , of the University of Chicago. Dr. Kanwar joins Digital Media Editor Van-Khue Ton, MD, PhD for a discussion about the special issue. The discussion explores: The importance of discussing device therapies in the advanced heart and lung failure communities The most anticipated device therapies in the pipeline for clinicians and patients to…
S6 · E7 · 1 Apr 2026 · 14 min
Episode 81: Lung Cancer after Lung Transplant
JHLT: The Podcast kicks off April with a discussion of the paper, " Lung Cancer After Lung Transplantation: Early Detection and Curative Surgery Drive Long-Term Survival ," which appears in the April issue of JHLT. Senior author Pauline Pradère, MD , of Hôpital Marie Lannelongue in Paris, joins the episode to talk about the paper. The conversation includes discussion of: The overall survival of patients who develop lung cancer after lung transplant—and the key differences between the cohort of patients who developed cancer versus the patients who did not Managing lung cancer in transplant…
S6 · E6 · 18 Mar 2026 · 18 min
Episode 80: Solid Organ Transplantation and HIV Infection
JHLT: The Podcast continues a themed month on HIV infection in solid organ transplant, building on our last episode's exploration from Dr. Saeed at Montefiore in New York. Our guest this episode is infectious diseases expert Cameron Wolfe, MD , Professor of Medicine at Duke University Medical Center. He joined us while on sabbatical with his family in Brisbane Australia for a conversation about how transplant centers now consider HIV infection, including transplant recipients who are HIV positive. The discussion explores: How the HOPE Act of 2013 changed practice in the United States, and…
S6 · E5 · 4 Mar 2026 · 19 min
Episode 79: Early Experience in Heart Transplantation Using Donors with HIV
This month on JHLT: The Podcast , the Digital Media Editors host two themed discussions around HIV in solid organ transplantation. The conversation begins with a discussion of the paper, " Early experience in heart transplantation utilizing donors with HIV ," which appears in the March issue of JHLT . First author Omar Saeed, MD, MSc , of the Division of Cardiology at Montefiore Medical Center in New York, NY USA, joins the episode. The conversation includes discussion of: The ethics and evolution of the Montefiore program's transplant eligibility and criteria The role of the HOPE Act in the…
S6 · E4 · 18 Feb 2026 · 12 min
Episode 78: Barriers and Opportunities in DCD Heart Transplantation
JHLT: The Podcast returns with an episode for our heart transplant colleagues, discussing the paper, " Barriers and opportunities in donation after circulatory death heart transplantation ," from the February issue of JHLT . Featured on this episode is first author, Katherine G. Phillips, MD , of the Department of Cardiothoracic Surgery at NYU Langone, and co-author, Brian Wayda, MD , from the Division of Cardiology at NYU Langone. The discussion explores: Geographic variability on DCD heart utilization—why it happens and how to address Concerns around donor progression to circulatory arrest…
S6 · E3 · 4 Feb 2026 · 22 min
Episode 77: ISHLT Consensus Statement: Short Telomere Syndrome and Lung Transplantation
In this episode of JHLT: The Podcast , the Digital Media Editors host a discussion on a new consensus statement from ISHLT on Short Telomere Syndrome (STS) and Lung Transplantation . The document was first published last month. They're joined by document leads Andrew Courtwright, MD, PhD , of the University of Pennsylvania in Philadelphia; Dr. John Mackintosh of Prince Charles Hospital in Brisbane; and John McDyer, MD , of the University of Pittsburgh Medical Center in Pittsburgh. The conversation includes discussion of: Recommendations for assessing patients for STS Which patients we should…
S6 · E2 · 21 Jan 2026 · 19 min
Episode 76: Evolocumab's Impact on Coronary Physiology and Microstructure in De Novo Heart Transplant Recipients
JHLT: The Podcast returns with an episode discussing the paper, " Impact of evolocumab on coronary physiology and microstructure in de-novo heart transplant recipients ," from the January issue of JHLT . Featured on this episode is early career guest host Bin Yang, MD , of Massachusetts General Hospital. Mentored by Digital Media Editor Van-Khue Ton, MD, PhD , Dr. Yang shares hosting duties this episode and brings great questions to the discussion. Drs. Yang and Ton are joined by the first author, Salma Karim , and senior author, Hans Eiskjaer , both from Aarhus University Hospital in…
S6 · E1 · 7 Jan 2026 · 14 min
Episode 75: A Look Back on 2025 in JHLT
Happy new year and welcome to a new season of JHLT: The Podcast ! In this year-end recap, the Digital Media Editors will each share one of their favorite studies from The Journal of Heart and Lung Transplantation in 2025. You'll get a look at some of the best science in advanced heart and lung failure from the past year. Studies featured: Efficacy and safety of sotatercept across ranges of cardiac index in patients with pulmonary arterial hypertension: A pooled analysis of PULSAR and STELLAR Gomberg-Maitland M, et al. JHLT Apr 2025 44(4):609 – 624. A consensus-based framework for the…
S5 · E19 · 17 Dec 2025 · 11 min
Episode 74: Outcomes for CTEPH patients with High Antiphospholipid Antibodies after Pulmonary Endarterectomy
JHLT: The Podcast returns with an episode discussing the paper, " High Antiphospholipid Antibody Titers and Outcomes of Pulmonary Endarterectomy: A Single-Center Retrospective Observational Cohort Study ," from the December issue of JHLT . They are joined by the first author, Camille Miard, MD , and senior author, François Stéphan, MD, PhD , both from the cardiothoracic intensive care unit at Hôpital Marie Lannelongue in Paris. The discussion explores: Whether antiphospholipid antibody titers could predict postoperative outcomes for CTEPH patients undergoing pulmonary endarterectomy (PEA)…
S5 · E18 · 3 Dec 2025 · 11 min
Episode 73: Lung Transplant in Patients with Suspicious Lung Lesions
On this episode of JHLT: The Podcast, the Digital Media Editors host a discussion on the paper, " Lung transplant in patients with suspicious lung lesions: A single-center retrospective data analysis ," which appears in the December issue of JHLT . They are joined by the senior author, Stefan Schwarz, MD, PhD , of the Department of Thoracic Surgery at the Medical University of Vienna. The discussion explores: Methods used to assess the probability of malignancy in the patient cohort The limitations of common scanning methods in assessing this type of transplant patient What the study…
S5 · E17 · 5 Nov 2025 · 20 min
Episode 72: Impact of Donor-Specific Antibodies on Longitudinal Lung Function and BLAD
On this episode of JHLT: The Podcast, the Digital Media Editors host a discussion on the paper, " Impact of donor specific antibodies on longitudinal lung function and baseline lung allograft dysfunction ." They are joined by the first author, Muhtadi Alnababteh, MD , Assistant Professor at the University of Maryland and Staff Clinician at the National Institutes of Health, and senior author Michael Keller, MD , of the Pulmonary and Critical Care division at the University of Maryland. The discussion explores: Common characteristics of patients who developed donor-specific antibodies (DSA)…
S5 · E16 · 15 Oct 2025 · 21 min
Episode 71: Cardiogenic Shock Working Group: Patients on Impella 5.5 for more than 14 days
On this episode of JHLT: The Podcast , the Digital Media Editors invite co-lead author Nir Uriel, MD , Director of Advanced Heart Failure and Cardiac Transplantation at New York Presbyterian Hospital and Professor of Medicine at Columbia University. Dr. Uriel joins to discuss the work of the Cardiogenic Shock Working Group (CSWG) and their recent paper, " Outcomes of patients supported on Impella 5.5 for more than 14 days: A Cardiogenic Shock Working Group registry analysis ." The discussion explores: Why patients on longer duration of MCS had better survival but maintained similar rates of…
S5 · E15 · 1 Oct 2025 · 16 min
Episode 70: Passive Leg Raise and Occult HFpEF in Pulmonary Hypertension
On this episode of JHLT: The Podcast, the Digital Media Editors invite author Dr. Ayumi Goda , from the Kyorin University Hospital in Tokyo, Japan, to discuss her team's paper, " Prevalence of occult HFpEF and age-specific efficacy of passive leg raise in pulmonary hypertension ." The discussion explores: How clinical observations led to the idea for a study on whether the passive leg raise could unmask occult HFpEF The potential diagnostic value of the passive leg raise in differing patient populations Age-specific cutoffs that may influence what kind of testing to use in clinical practice…
S5 · E14 · 3 Sep 2025 · 16 min
Episode 69: Optimal Pre-Transplant Duration with HeartMate III LVADs
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Ahmet Bilgili , from the University of Florida's Congenital Heart Center, and senior author Eric I. Jeng, MD , from the University of Florida's MCS program. Bilgili and Dr. Jeng discuss their paper, " Optimal pretransplant duration with HeartMate III left ventricular assist device: A contemporary analysis ." The discussion explores: Prior gaps in the literature regarding contemporary HM3 outcomes in relation to transplantation—and the study's potential influence on policy Which length of HM3 support…
S5 · E13 · 20 Aug 2025 · 13 min
Episode 68: DCD lung procurement in the UK
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Luke Williams , a cardiothoracic surgery trainee at Royal Papworth Hospital, NHS Blood and Transplant Clinical Research Fellow, and a PhD student at Cambridge University in the UK. Luke discusses his paper, " The United Kingdom's experience of controlled donation after circulatory death direct procurement of lungs with concomitant abdominal normothermic regional perfusion with an analysis of short-term outcomes ." The discussion explores: Requirements, regulations, and practices in the UK around DCD…
S5 · E12 · 6 Aug 2025 · 11 min
Episode 67: Metabolic and transcriptomic insights into temperature-controlled donor heart transportation
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Gaurav Sharma, PhD, MBA , from the University of Texas Southwestern Medical Center in Dallas. Dr. Sharma discusses his paper, " Metabolic and transcriptomic insights into temperature controlled hypothermic preservation of human donor hearts ." The discussion explores: How donor hearts not offered or declined for transplantation responded in hypothermic preservation versus conventional static cold storage Potentially beneficial genetic signatures yielded by TCHP versus cold storage The surprising response of…
S5 · E11 · 2 Jul 2025 · 15 min
Episode 65: Regional differences in primary graft dysfunction
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Joan Guzmán-Bofarull , and senior author, Marta Farrero , both of the Hospital Clinic de Barcelona in Spain. They join to discuss their paper, " Regional differences in primary graft dysfunction: A report from the international consortium on PGD ." The discussion explores: The international consortium on PGD, the composition of the study, and the practices of the included countries in the United States, Canada, and Europe Hypotheses on why the study shows better 30-day and 1-year outcomes in the United States…
S5 · E10 · 19 Jun 2025 · 13 min
Episode 65: Refining the grading of mild CAV
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Nikil Prasad, MD , a cardiology fellow in the Columbia University Medical Center in New York, to discuss the paper, " Can the grading of mild cardiac allograft vasculopathy be further refined? An angiographic and physiologic assessment of heart transplant recipients with ISHLT CAV 1 ." The discussion explores: The study's subdivisions of CAV grade 1 into CAV 1a and CAV 1b, based on the degree of coronary stenosis Differing clinical information provided by different methods of CAV screening: reduced myocardial…
S5 · E9 · 22 May 2025 · 8 min
Episode 64: A look back at ISHLT2025
On this special episode of JHLT: The Podcast , the Digital Media Editors take a look back at the exciting science that was on display at ISHLT2025, the ISHLT 45 th Annual Meeting & Scientific Sessions. Topics include: Telomere biology disorders and lung transplantation The meeting's special focus on cardiogenic shock The apixiVAD trial exploring low dose apixaban in HeartMate 3 LVADs Myocardial recovery on durable LVADs For the latest studies from JHLT , visit jhltonline.org/current , or, if you're an ISHLT member, access your Journal membership at ishlt.org/jhlt . Full-text abstracts of the…

About JHLT: The Podcast

The Journal of Heart and Lung Transplantation podcast airs each month and features the JHLT Digital Media Editors in round table talks with the Journal's contributors.

JHLT: The Podcast is a English tech & science podcast from ISHLT. Melo plays each episode straight from the publisher's own feed — no ads added, no account needed — and remembers where you stopped, in this browser only.

Publisher: ISHLT
Language: English
Category: Tech & Science
New episodes: Every two weeks
Typical length: 14 min
Latest episode: 7 Oct 2026
Feed: RSS — paste into any podcast app
Apple Podcasts: podcasts.apple.com/podcast/id1547629587

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