Free-Threaded Python's History & uv in Production

More from The Real Python Podcast

1. 

   E306 · 7 Aug 2026 · 1 hr 6 min

   Programmatically Developing LLM Prompts With DSPy

   How can you move from manually writing prompts for an LLM application toward defining them programmatically? This week on the show, Brett Kennedy returns to discuss his new book "Building LLM Applications with DSPy."

2. 

   E305 · 31 Jul 2026 · 57 min

   Should You Understand Your Entire Python Codebase?

   Should you understand the entirety of your codebase? How familiar are you with Python's built-in functions? Christopher Trudeau is back on the show this week with another batch of PyCoder's Weekly articles and projects.

3. 

   E304 · 24 Jul 2026 · 58 min

   Configuring a Versatile LLM Harness & Scraping the Web With Scrapy

   Which is more important, the model or the "harness" around an LLM? What are ways to assemble an efficient agentic developer workflow? This week on the show, Ayan Pahwa joins us to discuss harnessing, web scraping, and self-hosting Python applications.

4. 

   E302 · 10 Jul 2026 · 59 min

   Constructing and Judging Modern Agentic Workflows

   How can you improve your LLM agent systems through specification enrichment? What are the advantages of having an LLM act as a judge within an agent system? This week on the show, Senior IEEE Member and Quality Engineer Suneet Malhotra joins us to discuss building and evaluating agentic architecture.

5. 

   E301 · 3 Jul 2026 · 46 min

   Running Python Locally in a Sandbox

   How do you avoid the risk of running a Python application locally that could be malicious, break your code, or leak private data? How can you create a sandboxed local environment using WASM and MicroPython? Christopher Trudeau is back on the show this week with another batch of PyCoder's Weekly articles and projects.

6. 

   E300 · 26 Jun 2026 · 47 min

   Maintaining Your Python Developer Instincts While Using LLM Tools

   Do you feel like your Python skills are atrophying after using LLM coding tools? How do you add the right kind of friction into your coding routine to keep your developer instincts sharp? Christopher Trudeau is back on the show this week with another batch of PyCoder's Weekly articles and projects.

7. 

   E313 · 2 Oct 2026 · 44 min

   Python 3.15: Exploring the New Features

   Python 3.15 is (almost*) here! Christopher Trudeau and Bartosz Zaczyński return to discuss the new version. Bartosz coordinated the series of preview articles with members of the Real Python team and wrote the showcase tutorial, "Python 3.15: Cool New Features for You to Try." Christopher's video course "What's New in Python 3.15" covers the topics from the article and shows the new features in action.

8. 

   E312 · 25 Sep 2026 · 1 hr 8 min

   Navigating AI in Open Source: Insights From Wagtail

   How should you manage AI contributions to an open-source project? How do you measure the impact of using AI tools for development, and what generative features do end users want from a content management system? This week on the show, we speak with Thibaud Colas and Meagen Voss from Wagtail about the complex considerations software organizations are currently facing.

9. 

   E311 · 11 Sep 2026 · 47 min

   Django Developers Survey Results & Reproducible Python Builds

   What are the latest trends uncovered in the 2026 Django Developers Survey? How are Django users employing LLMs in their development process? Christopher Trudeau is back on the show this week with another batch of PyCoder's Weekly articles and projects.

10. 

    E310 · 4 Sep 2026 · 1 hr 17 min

    Performance Engineering: Profiling and Making Apps Fast by Default

    How do you plan for the performance of your Python applications? What does a performance budget entail, and where should you spend your resources? This week on the show, we speak with Den Odell about his new book "Fast by Default: Practical Performance Engineering."

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