Gastroenterology to-go! The UEG Podcast covers scientific, educational and professional development topics within the digestive health community. Listen as our two international experts (Egle Dieninyte-Misiune, Lithuania and Pradeep Mundre, UK) cover a wide array of timely, multidisciplinary topics
Around half of patients with pancreatic cancer are diagnosed after the disease has already spread. Dr Pilar Acedo Nuñez from UCL joins Eglė Dieninytė to discuss screening and why we still rely on CA 19-9, what the new RAS inhibitors could mean for patients, whether molecular profiling should be routine, and what the first-in-human KRAS vaccine trial has shown in people at high risk of pancreatic cancer. Part 2 will look at treatment options.
Rome V was published ten years after Rome IV. Maura Corsetti, co-chair of the Rome V Bowel Disorders committee, joins Pradeep Mundre to discuss the relaxed IBS criteria, three new adult diagnoses, the split between research and clinical criteria, and why explaining a gut-brain diagnosis early spares patients repeat investigation.
Flares, surgery and the postpartum period. Mette Julsgaard and Pradeep Mundre on whether active disease or a JAK inhibitor is the bigger risk, starting upadacitinib at 28 weeks, acute severe colitis and when to operate, vaccinating infants exposed to biologics.
Mette Julsgaard and Pradeep Mundre on IBD before and during pregnancy: what active disease costs in fertility, what to check at the preconception visit, and a drug by drug run through of what to stop, continue and start, from 5-ASAs and thiopurines to biologics and JAK inhibitors, as well as the use of low-dose aspirin.
Operate on every high-risk early oesophageal cancer after endoscopic resection and more than 80% of those patients gain nothing. Roos Pouw, Ana-Maria Bucalau and Jessie Elliott on strict endoscopic follow-up, the shift from chemoradiation to perioperative FLOT, and what ENSURE showed about surveillance after oesophagectomy.
UEG Podcast is on summer holiday and re-releases published episodes that we think deserve another listen. Enjoy! In this episode of the UEG Talks conversation between Maria Vehreschild and Pradeep Mundre, we delve into the complexities of the faecal microbiome and the role of faecal microbiota transplantation (FMT) in treating various diseases, particularly C. difficile infections and inflammatory bowel disease (IBD). The discussion covers the historical context of FMT, its mechanisms of action, current treatment guidelines, safety considerations, and the various delivery methods. The…
UEG Podcast is on summer holiday and re-releases published episodes that we think deserve another listen. Enjoy! Functional gastrointestinal disorders, or disorder of gut-brain interaction, can be frightening to many GIs. How do I talk to the patient? What can I tell them if there is no improvement in their symptoms? How can I even explain to them what their diagnosis is, if I don’t even know it? To clear things up and provide clear points of action, our host Egle Dieninyte talked to Tim Vanuytsel from the University Hospital in Leuven, Belgium.
UEG Podcast is on summer holiday and re-releases published episodes that we think deserve another listen. Enjoy! In this episode, host Egle speaks with former UEG President Axel Dignass about what it takes to lead in times of crisis. Drawing on his experience during the COVID-19 pandemic, Axel reflects on the difference between being a boss and being a true leader. He shares thoughts on the value of empathy, transparency, and consistency, as well as how to build and sustain a resilient team. The conversation also touches on the challenges of going virtual, the importance of recognising team…
Michael Bretthauer on the real epidemiology of colorectal cancer in the under-50s: a genuine rise from a tiny baseline, the carcinoid confounder inflating the numbers, lifestyle versus genetics, why screening ages shouldn't drop yet, and the ECOPOP trials testing endoscopic resection against surgery.
The 2024 MASLD treatment guidelines are already changing. Pradeep Mundre and Professor Sven Francque (Antwerp), guideline co-author, cover weight-loss targets (7% and 10%), resmetirom in F2-F3 fibrosis, semaglutide's positive phase 3 in MASH, plus pioglitazone, bariatric surgery, and liver transplantation in this population.
Around one in three adults has MASLD, but only a few percent reach cirrhosis. Pradeep Mundre and Professor Sven Francque (Antwerp), co-author of the 2024 EASL guidelines, cover the new nomenclature, dysfunctional adiposity versus BMI, and how to use FIB-4 to decide who needs a hepatologist.
Sphincter-preserving surgery spares most rectal cancer patients a stoma, but hands many of them low anterior resection syndrome (LARS). Three European surgeons join Harald Rosen in discussing follow-up, where transanal irrigation lands, when to involve the gastroenterologist, and where sacral neuromodulation fits.
EoE requires long-term management, but what does that look like in practice? In Part 2, Prof. Alex Straumann discusses the realities of treating a chronic, relapsing disease, where remission is achievable but a cure is not. The episode explores how to approach maintenance therapy, manage persistent symptoms despite histological remission, and when to escalate treatment to biologics. It also addresses the practical limitations of dietary strategies and the ongoing challenge of identifying trigger foods. Looking ahead, the discussion highlights key unmet needs in EoE, including the absence of…
Part 2 will be released on Wednesday, the 29th of April. Eosinophilic oesophagitis (EoE) is now a well-recognised condition. But it was not always so. In this episode, Prof. Alex Straumann shares how EoE was first identified, taking us back to the late 1980s when unusual cases of food impaction and eosinophilic inflammation did not fit any known diagnosis. He discusses the clinical observations that led to recognising EoE as a distinct disease, the early case series that defined its phenotype, and the initial treatment approaches that shaped current practice. The episode also addresses key…
In this episode, Pradeep Mundre speaks with Hannah Gordon about one of the most challenging areas in inflammatory bowel disease management: balancing effective treatment with cancer risk. As therapeutic options expand, clinicians increasingly face complex scenarios involving patients with prior malignancy in remission or those undergoing active cancer treatment. The discussion examines how cancer risk relates both to IBD itself and to immunosuppressive or biologic therapies. The episode highlights limitations in current evidence, differences across drug classes, and the importance of…
Cristian Costas, a leading dietitian in coeliac disease, shares insights on managing celiac disease through diet, setting up specialised services, and navigating dietary challenges. We explore diagnosis, implementation of a gluten-free diet, and strategies to improve patient outcomes.
In the second part of this in-depth conversation, host Egle Dieninyte continues her discussion with Professor Nageshwar Reddy, shifting the focus from technological innovation to ethics, responsibility and the human dimension of endoscopy. Professor Reddy shares how mobile endoscopy units have brought life-saving care to rural populations, and why cascade hygiene strategies are sometimes necessary when resources are limited. The conversation then turns to a topic rarely discussed openly: mistakes. What constitutes a true medical mistake? How do we distinguish adverse events from preventable…
What has truly transformed endoscopy over the past decades? In this first part of a two-part conversation, host Egle Dieninyte sits down with Professor Nageshwar Reddy, one of the most influential pioneers in modern therapeutic endoscopy, to reflect on how the field has evolved — and where it is heading next. From the transition from rigid to fibreoptic endoscopy, to the introduction of video systems that reshaped team dynamics in the endoscopy suite, Professor Reddy explains why some of the most powerful innovations were not necessarily the most glamorous ones. The discussion also explores:…
- What happens when optical diagnosis and histology don’t align? - Does better polyp detection always mean better outcomes? - And how should AI, quality metrics and surveillance intervals really shape daily endoscopy practice? In this special episode, we share an unfiltered round-table discussion recorded during the UEG Online Course on the impact of polyp detection in colonoscopy. Leading experts Raf Bisschops, Manuele Furnari, Veronique Van der Voort and Pieter Sinonquel debate real-world dilemmas around serrated lesions, pathology discordance, documentation, bowel preparation and the…
In this episode of the UEG Podcast, host Pradeep Mundre is joined by David Sanders, Professor of Gastroenterology at Sheffield and one of the world’s leading experts in coeliac disease. Timed with the recent update of the British Society of Gastroenterology coeliac guidelines, the discussion explores why coeliac disease remains frequently underdiagnosed, even in specialist care. Together, they unpack the latest evidence on serology-based diagnosis, optimal biopsy strategies, potential and seronegative coeliac disease, and when HLA testing is truly useful. The episode also covers long-term…
Immunotherapy might be revolutionising the way we fight GI cancers. In our latest episode, we dive into how this innovative treatment is changing patient outcomes and the role it plays in cancer management. To discuss this, we talked to Jeroen Dekervel, gastroenterologist and oncologist at the UZ Leuven in Belgium. Our host, Pradeep Mundre guides us through the conversation about how tumours develop a resistance to chemotherapy, the quality of life for oncological patients, and why the term "palliative treatment" for cancer patients could use an update.
In this thought-provoking episode of the UEG Podcast, host Egle Dieninyte sits down with organisational psychologist Lina Sopiene to explore one of medicine’s most unspoken challenges — burnout. Together, they unpack why high-achieving healthcare professionals often equate self-worth with performance, how this mindset fuels exhaustion, and what practical steps can help doctors and nurses reconnect with themselves. From learning to “be a human being, not just a human doing” to managing workplace anger and setting healthy boundaries, this conversation is a candid look at the emotional…
This episode of the UEG Podcast takes place at the EPC meeting in the summer of 2025. Our host Egle Dieninyte sits down with Professor Marco Del Chiaro, Surgical Oncologist and global lead of the upcoming Guidelines on Pancreatic Cystic Neoplasms. Tune in as they discuss why a unified, evidence-based approach is essential in this complex field, the challenges of managing cystic pancreatic lesions with limited high-quality data, and the balance between clinical judgement and guideline recommendations. Professor Del Chiaro also reflects on the limitations of current evidence, the evolving role…
In this episode of the UEG Podcast, Mary Phillips and Leigh Donnelly reflect on the highlights of UEG Week 2025 in Berlin from a nursing and allied healthcare perspective. They discuss the most inspiring sessions from learning through mistakes in “Never Waste a Good Disaster” to the growing focus on sustainability, green endoscopy, and global health. The conversation also touches on caring for trans patients in gastroenterology, tackling fake news in dietetics, and understanding the clinical impact of GLP-1 medications and pancreatic cancer research. With insights on teamwork, education, and…
In this episode, UEG's new Scientific Committee chair Jörn Schattenberg and Carolin Schneider, UEG rising star of 2025, recap the standout science from UEG Week 2025 in Berlin. They discuss highlights from the HPB field, including pivotal phase III data on linerixibat for cholestatic pruritus in PBC, advances in MASLD/MASH therapies such as FGF21 analogues and resmetirom, and new insights into liquid biopsy and AI-assisted imaging for pancreatic lesions. The conversation also explores simvastatin’s potential in preventing recurrent pancreatitis and reflects on the value of collaboration,…
In this episode of the UEG Podcast, our host Pradeep Mundre, together with IBD expert Klaartje Bel Kok, explore the latest breakthroughs in IBD presented at UEG Week 2025 in Berlin. From long-term IL-23 inhibitor data to novel drugs such as Obefazimod and Tulisokibart, the discussion covers key findings that are reshaping IBD management. Bel dives into new insights on JAK inhibitors in pregnancy, the growing role of ultrasound monitoring in IBD, and the challenge of choice overload in treatment decisions. Tune in for expert reflections on emerging research, collaboration within the IBD…
Join Julia Mayerle and Francisco X. Real (Paco) as they reflect on the first-ever Digestive Disease Mechanism (DDM) Summit, introduced during UEG Week 2025 in Berlin. In this special episode, they discuss how the DDM Summit brought together leading scientists and clinicians to explore the mechanisms driving GI cancers — from colorectal to pancreatic and liver cancer. Hear how cutting-edge discoveries in genomics, metabolism, and tumour microenvironment are already shaping translational research and clinical trials. Julia and Paco also share highlights from the meeting, including exciting…
In this episode, host Eglė is joined by Manmeet Matharoo (St Mark’s Hospital, London) to reflect on the highlights of UEG Week 2025 in Berlin from an endoscopy perspective. Together, they discuss the shift towards precision endoscopy, smarter patient and lesion selection, and the philosophy of “treat the patient, not the polyp.” The conversation explores how concepts such as cold-snare resection, training quality assurance, and green endoscopy are shaping modern practice. They also touch on leadership, mentorship, and the medical community’s role in tackling misinformation online — a…
Our hosts Egle and Pradeep take you back to UEG Week 2024 in Vienna, where they spoke with visitors from across the globe. Discover their impressions, experiences, and highlights — from career-boosting opportunities to inspiring scientific sessions and the vibrant community spirit. Tune in and get ready for what awaits at UEG Week 2025 in Berlin. Don’t miss the chance to hear why participants call UEG Week a “must” every year!
How can we ensure young patients with chronic digestive and liver diseases move safely and smoothly from paediatric to adult care? In this episode, Pradeep speaks with Professor Patrizia Burra (University of Padua, Italy; Chair of UEG Public Affairs Group) and Dr Jorge Amil Dias (Hospital Lusíadas, Porto, Portugal; ESPGHAN representative in UEG Public Affairs Committee).
About UEG Podcast
Gastroenterology to-go! The UEG Podcast covers scientific, educational and professional development topics within the digestive health community. Listen as our two international experts (Egle Dieninyte-Misiune, Lithuania and Pradeep Mundre, UK) cover a wide array of timely, multidisciplinary topics
UEG Podcast is a English tech & science podcast from UEG United European Gastroenterology. Melo plays each episode straight from the publisher's own feed — no ads added, no account needed — and remembers where you stopped, in this browser only.
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