Podcast · Arts & Books

Chemist Confessions

by Chemist Confessions Inc. · English · Arts & Books

Skincare chemists Gloria & Victoria’s weekly conversation on all things skincare science. The podcast covers notable skincare news, decoding outrageous claims, demystifying the overwhelming product landscapes, and answering your burning skincare questions. Tune in if you might need help building a s

New episodes: Weekly
Typical length: 39 min
Latest: 9 Oct 2026
Language: English

Latest episode

9 Oct 2026 · 56 min

#191) Decoding Peptides with DECIEM's Rita Silva: What Does the Science Say?

In this special episode, we're joined by Rita Silva, Acting Director of Scientific Communications at DECIEM, for a deep dive into the science behind The Ordinary's popular peptide serums. From Multi-Peptide and Matrixyl to Argireline and the latest plant-derived growth factors, we're getting into the formulation history, clinical research, and what these products can realistically do for your skin.And of course, we have to tackle some of your biggest peptide questions. Can you mix copper peptides with vitamin C? Are peptide serums worth adding to a retinoid routine? And where should a…

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Earlier episodes 29 most recent

E190 · 18 Sep 2026 · 36 min
#190) Chemists Test 7 CE Ferulic Dupes vs. the Original
PLEASE NOTE: In this episode, the original Skinceuticals CE Ferulic formula with only 15% ascorbic acid, 1% tocopherol, and 0.5% ferulic acid was tested for this episode. We dive into part two of our vitamin C series by putting popular C E Ferulic dupes to the test. Before revealing our side-by-side stability results, we go through a very helpful study from Slovenia examining 41 finished vitamin C products using HPLC testing to compare the quirks of various vitamin C derivatives—including L-ascorbic acid, ascorbyl glucoside, sodium ascorbyl phosphate, and 3-O-ethyl ascorbic acid. Then we go…
E189 · 11 Sep 2026 · 44 min
#189) Is the updated CE Ferulic worth the $$$$?
We dive into a science-heavy breakdown of vitamin C formulations, focusing on the recent updates to the gold-standard C E Ferulic serum. We explore the history of L-ascorbic acid efficacy studies dating back to the 1990s by Dr. Pinnell’s lab, highlighting the classic UV-induced erythema protocol used to validate antioxidant skin protection. Then, we analyze emerging clinical data around new CE Ferulic additions: carnosine and dandelion endophytol and discuss the available data to see if the chemists can figure out whether or not this is worth the Skinceuticals price tag. 00:00 | Intro! 03:15…
E187 · 27 Aug 2026 · 49 min
#188) We sat down with founder of Soko Glam: Charlotte Cho!
Check out Soko Glam: Check out our products: https://sokoglam.com/collections/chemist-confessions?_pos=1&_psq=chemist+confessions&_psid=080163648&_ss=eIn celebrating our arrival on Soko Glam, we sat down with founder Charlotte Cho to dive deep into the real science, mechanics, and formulation realities behind K-Beauty. We break down the evolution of multi-step routines, the truths behind product categories like toners and essences, and why classic ingredients like snail mucin continue to hold up under scientific scrutiny. From the manufacturing hurdles of hot-pour cleansing balms to…
E188 · 21 Aug 2026 · 25 min
#187) Decoding Dr. Reju-All's PDRN & Copper Peptide #ad
#sponsored We’re taking a deep dive into the science behind K-Beauty brand Dr. Reju-All! In this sponsored episode, we've partnered with Dr. Reju-All, to share some of their testing behind the products: the Advanced PDRN Rejuvenating Cream and their latest launch, the Advanced PDRN Copper Peptide Serum. We discuss their PDRN ingredient sourcing and why higher concentrations aren't always better—highlighting in vitro and clinical data showing why 1,200 ppm of salmon-derived PDRN is an optimal sweet spot for barrier recovery and hydration. We also analyze their Advanced PDRN Copper Peptide…
E186 · 18 Aug 2026 · 37 min
#186) 5 Copper Peptide Serums Tested
We’re cutting through the marketing fluff to decode five popular copper peptide serums! In this episode, we analyze the formulas, active ingredient combinations, and clinical data behind products from the Remedy, COSRX, Dr. Reju-All, The Ordinary, and Peach & Lily. We break down what these serums intend to treat, highlight potential formula overlap (like sneaky niacinamide and bakuchiol), and discuss the layering rules you may need to consider for your routine. Hear the chemists' perspective on where peptides fit into a smart anti-aging strategy. Timestamps 00:01 | Copper Peptide Formula…
E185 · 14 Aug 2026 · 38 min
#185) Are Copper Peptides (GHK-Cu) OVERRATED?
🧪 Is GHK-Cu Overrated? The Science of Copper Peptides Explained Are Copper Peptides (GHK-Cu) actual anti-aging powerhouses, or just smart marketing hype? In this video, we dive deep into the 50-year scientific history of GHK-Cu, breaking down the exact biological pathways behind collagen and elastin synthesis. We analyze the physiological realities of peptide size, molecular weight, and the famous 500 Dalton Rule to reveal how much of your product actually penetrates the skin barrier. And most importantly... all the theories and in vitro studies aside, what do the clinical studies REALLY…
E184 · 7 Aug 2026 · 32 min
#184) Are You Applying Enough Sunscreen correctly?
Description: We are tackling our top 10 sunscreen takeaways after four straight years of testing dozens of formulas in our 3430 series! From figuring out how much SPF you actually need to apply (and why we rating-split over the infamous Rich Area Hold Cream), we get into all the messy details. We also dive into eye-area stinging, why US mineral sunscreens hit differently, layering under makeup, handling acne flare-ups, and finding out if dropping to SPF 30 actually gives you better texture.Timestamps 00:01:05 | How Much Sunscreen Should You Actually Apply? 00:03:22 | Why Did the Rich Area…
E183 · 31 Jul 2026 · 39 min
#183) Testing 30 sunscreens in 30 days: US CHEMICAL SUNCREENS | Chemist Confessions Podcast
WE ARE BACK! Our 30 for 30 sunscreen challenge continues by diving into the wild world of US chemical sunscreens! In this episode, we break down 13 different formulas—categorized by price point from budget-friendly drugstore finds to eye-watering luxury formulas. TIMESTAMPS: 00:31 | US Chemical Sunscreens Overview 01:30 | Economical & Drugstore Sunscreens 05:11 | Neutrogena Sport Face SPF Review 07:01 | Testing Vacation Sunscreen & Pilling Issues 09:45 | Eucerin Tinted Chemical Sunscreen 13:05 | e.l.f. Suntouchable Silicone Texture 15:35 | Anua Invisible Matte & Numbuzin SPF 25:14 | Sephora…
E182 · 14 Jul 2026 · 44 min
#182) PART 2! 30 SUNSCREENS IN 30 DAYS! - EU and Asia
We are wrapping up the next leg of our #30for30 sunscreen challenge testing roundup! In this episode, we dive deep into the world of international sunscreens, putting five popular EU formulas and eight Asian sunscreens to the test. Plus, don't miss a hilarious, science-backed detour into the sophisticated culinary habits of cockatoos!Products Mentioned: • Avene Anti-Pigmentation Tinted Fluid https://go.shopmy.us/p-64086387 • La Roche Posay UVMune Tinted Fluid https://go.shopmy.us/p-67227007 • La Roche Posay UV Air Serum https://go.shopmy.us/p-71463108 • Geek & Gorgeous Zero Feel…
E181 · 9 Jul 2026 · 23 min
#181) WE TESTED 30 SUNSCREENS IN 30 DAYS! P1 - US Sunscreen
The #30for30 Sunscreen Challenge is back, and we are officially kicking off our deep dive! In this episode, we’re breaking down the US mineral sunscreens we put to the test. From "accidental" foundations and heavy-duty rub-ins to luxury formulas that claim to erase wrinkles, we’re giving you the unfiltered truth on what’s worth your cash and what you should pass on. Grab your SPF, and let's get into the reviews! Timestamps 0:00 - Intro 0:45 - Missha Perfect Cover: hybrid formula that's better as a foundation than standalone sunscreen 02:15 - Merit The Uniform: A solid coverage - SPF usage…
E180 · 25 Jun 2026 · 57 min
#180) What to look for in a sunscreen?
Sunscreen database: https://chemistconfessions.com/sunscreen Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 Shop more of my favorite products here: https://shopmy.us/chemistconfessions Instead of getting bogged down by marketing fluff, we dive deep into the real metrics of sunscreen performance: initial application speed, the science behind "watery breaks," and how a product's long-term finish affects different skin types. Listeners will walk away knowing exactly how to spot uneven film formation, navigate the nuances of water and friction…
E179 · 16 Jun 2026 · 51 min
#179) EWG & Yuka App Debunked!
Sunscreen database: https://chemistconfessions.com/sunscreen Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 Shop more of my favorite products here: https://shopmy.us/chemistconfessions We are deep in sunscreen season, but unfortunately, it is also fear-mongering season. In this episode, we take a scientific look at prominent clean beauty advocacy voices like EWG and the Yuka app to untangle the science from the marketing fluff. We pull back the curtain on how these platforms analyze formulations, revealing why their extreme stances and rigid rating…
E178 · 5 Jun 2026 · 47 min
#178) 5 More Tinted SPFs Tested in 2026
Sunscreen database: https://chemistconfessions.com/sunscreen Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 Shop more of my favorite products here: https://shopmy.us/chemistconfessions We are starting of this series with tinted sunscreens. Navigating this category can feel like an existential crisis because these formulas are highly dependent on specific skin types and coverage needs. In this episode, we categorize this year's contenders by pigment level—ranging from completely sheer fluids to high-coverage, foundation-like hybrids, while analyzing…
E177 · 28 May 2026 · 43 min
#177) We must talk about IRON OXIDES!
We are officially diving into the sunscreen segment to break down a burning, highly technical question for anyone tackling stubborn dark spots: is iron oxide a non-negotiable must-have for your hyperpigmentation routine? Sunscreen database: https://chemistconfessions.com/sunscreen Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 Shop more of my favorite products here: https://shopmy.us/chemistconfessions
E176 · 7 May 2026 · 35 min
#176) We tested these lineup of viral PDRN products!
We are reviewing five popular K-Beauty products to see if they actually live up to the hype. We break down the science behind different PDRN sources, explore the "50 peptides" marketing claims, and analyze clinical data to separate realistic skin improvements from clever lighting tricks. You will learn how these products perform on different skin types—from "sticky and drying" textures to clinical-grade results—so you can decide which formulas are worth your routine and which are just "science-flavored" fillers.Shop other products tested on the CC podcast here:…
E175 · 30 Apr 2026 · 45 min
#175) Reviewing 2 Exosome Products!
We take an objective look at two polar opposite formulas—a $20 "junior" product and a $250 luxury serum—to see if the high science matches the high price tag. We break down the mysteries of sourcing, discuss why your 1% active might not be what it seems, and share our honest (and sometimes smelly) trial experiences. Whether you’re looking for genuine rejuvenation or just want to avoid lighting $500 on fire, we’ve got the data you need to navigate this rapidly changing landscape. Products Mentioned: Shop everything mentioned in this video here: https://shopmy.us/collections/4698294 Check out…
E174 · 23 Apr 2026 · 39 min
#174) PDRN Skincare: Longevity Cure or Just Hype?
Chemist Confessions Minis! https://chemistconfessions.com/shop/kits&minis We're pickup where we left off with another science update episode! Today, we're diving into another buzzy ingredient in the "longevity" space: PDRN. In this episode, we go beyond the "salmon sperm" headlines to investigate the latest science update on plant-derived PDRN from peony & rose, discuss the potential impact of molecular weight, and discuss early looks of unique PDRN delivery systems. Let's navigate the complex clinical data behind these DNA fragments and see if they actually match up to the marketing hype.…
E173 · 16 Apr 2026 · 46 min
#173) How About Exosomes in Skincare Now? (A 2026 Update)
Exosome is that $500 buzzword that's not going anywhere anytime soon. The claims have only gotten broader from healing, skin regeneration, eczema, anti-aging, to even alopecia. In this episode, we provide an update on any new data since our last deep dive last year. We discuss how these tiny lipid nanovesicles—ranging from 30 to 200 nanometers—function as "biological mail" that triggers collagen synthesis and other regenerative pathways. But do the theories really convert to proven topical benefits? We also tackle one of the most important things you should know about exosomes - sourcing.…
E172 · 9 Apr 2026 · 33 min
#172) THEY CLAIM THIS WILL WORK! Reviewing Retinal products!
In this episode, we are diving deep into the retinal (retinaldehyde) landscape to see how current market offerings stack up. Following our technical breakdown of retinol versus retinal, we shift our focus to real-world testing of popular formulations from Krave Beauty, Prequel, Celimax, and Medik8. We examine the scientific validity of concentration ranges—from the entry-level 0.05% to the more intense 0.24%—and discuss how different textures and price points impact the user experience for various skin types. Whether you are a retinoid rookie or a seasoned pro, we provide the detailed…
E171 · 1 Apr 2026 · 37 min
#171) We have to talk about this again: RETINOL VS RETINAL
We are diving back into the "rumor mill" of the retinoid world! Is Retinal actually better than Retinol, or is it just better marketing?In this episode, we revisit the Retinol vs. Retinal debate with new 2026 data. We break down what the evidence says about the retinoid conversion pathway into retinoic acid. We look at the latest clinical evidence to help you decide if it’s time to switch your anti-aging active or stay the course with your current skincare routine. Episode Timestamps0:00 - Intro: Revisiting the Retinoid Rumor Mill1:34 - Why Retinal (Retinaldehyde) is Growing in…
E170 · 25 Mar 2026 · 24 min
#170) WE ARE ENDING THIS! Hyperpigmentation Finale!
We are taking a break from hyperpigmentation actives! In this finale, we tie together months of research to help you build the ultimate hyperpigmentation skincare routine.We rank the actives from our last 10 episodes—including Hydroquinone, Azelaic acid, Arbutin, Glutathione, Thiamodol, Symwhite, etc. —from S-Tier (Gold Standard) to Tier “Meh.” We also filter through the 18 products we tested down to the ones we think should be on your radar and warn you about "Niacinamide Overload." Timestamps:0:00 - Intro: Our Hyperpigmentation Journey Recap1:34 - How to Build a Hyperpigmentation Routine…
E168 · 17 Mar 2026 · 37 min
#169) Reviewing Resorcinol stuff!
CHECK OUT DOUBLE PLAY!: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment We follow up our deep dive into resorcinols by featuring five specific products that highlight these key ingredients for hyperpigmentation! Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the…
E169 · 12 Mar 2026 · 26 min
#168) Resorcinol Part 2!
CHECK OUT DOUBLE PLAY!: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment We are wrapping up our hyperpigmentation series by diving into the science of resorcinol and its various derivatives. We explore the history of this "ancient" molecule, its uses in treatments like designer peels and acne prescriptions, and why the industry has shifted toward modern derivatives to avoid skin irritation. 00:21 | Part 2: Continuing our Resorcinol Series 00:35 | What is Hexylresorcinol? 00:49 | Hexylresorcinol vs. 2% Hydroquinone: The Study Breakdown 01:07 | Testing Parameters:…
E167 · 10 Mar 2026 · 24 min
#167) Resorcinol! (But really its cousins)
CHECK OUT DOUBLE PLAY!: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment We are wrapping up our hyperpigmentation series by diving into the science of resorcinol and its various derivatives. We explore the history of this "ancient" molecule, its uses in treatments like designer peels and acne prescriptions, and why the industry has shifted toward modern derivatives to avoid skin irritation. 01:28 | What is resorcinol? 01:50 | Resorcinol in acne treatments and designer peels 02:13 | Why is resorcinol used in hair dyes? 02:33 | The shift toward resorcinol…
E166 · 27 Feb 2026 · 42 min
#166) Reviewing 5 Glutathione Products!
We are back for a follow-up to our glutathione deep dive! We review five specific glutathione-heavy products, four from the K-beauty world and one popular Amazon find, to see if they truly deliver on their antioxidant and brightening claims. 00:00 | Intro: Hashtags & antioxidant claims00:24 | Welcome back to Chemist Confessions Podcast00:30 | Glutathione deep dive follow-up00:56 | Product lineup: 4 K-beauty + 1 Paula’s Choice02:05 | Price points & supply differences03:40 | Texture notes: neutral, not hydrating05:03 | Fragrance issues & masking glutathione scent06:05 | Stability concerns &…
E165 · 19 Feb 2026 · 35 min
#165: We are finally talking about this ingredient: GLUTATHIONE!
WE HEARD YOU! We explore the science behind one of the most requested and hyped ingredients skincare sector: glutathione. We break down what this "master antioxidant" actually is. 01:25 | What is Glutathione? Breaking down the tri-peptide 01:54 | Why is it called the "Master Antioxidant"? 02:43 | Mechanisms: Tyrosinase inhibition and skin whitening 03:16 | The Stability Struggle: Why pH and temperature matter 06:18 | Half-life study: How quickly does it degrade in your products? 08:12 | Gold Standard Age Booster: Tactical hyperpigmentation tool 08:40 | Does it actually work? Reviewing…
E164 · 12 Feb 2026 · 30 min
#164) The Drugstore Level Alpha Arbutin Landscape
We explore the science of skincare as we review five affordable, drugstore-priced arbutin products. In this episode, we break down everything from texture and clinical claims and ingredient lists of popular brands to help you find the right formula for your skin. TIMESTAMPS: 01:27 | Texture Analysis: Why is Arbutin so Sticky?03:01 | Texture Face-Off: Oily vs. Dry Skin Reactions04:48 | Is the Beauty of Joseon Serum a Moisturizer?06:01 | Chemist Notes: Breaking Down the Cosrx Formula06:57 | Analyzing Clinical Claims: Inner and Outer Melanin?09:57 | Instrumental Measurements: Reducing Dark…
E163 · 5 Feb 2026 · 40 min
#163 ) The Science of Arbutin: Does It Actually Clear Dark Spots?
We are diving deep into the science of skincare to explore the role of Arbutin in treating hyperpigmentation. In this human conversation, we break down what exactly Arbutin is, analyze the existing data on its efficacy, and provide a comprehensive guide on what you should consider when shopping for these products. Product Shoutout: Double Play Retinol Face and Eye Treatment:https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams?…
E162 · 28 Jan 2026 · 39 min
#162 ) Testing 3 Popular K-Beauty Azelaic Acid Serums
In this episode, we take a deep dive into the world of K-beauty azelaic acid products. We explore the science behind three popular contenders—Anua, Purito, and medicube—while decoding their ingredient lists, analyzing clinical testing data, and discussing the tricky chemistry of azelaic acid solubility. We provide a chemist’s perspective on how to choose the right formula for your skincare routine. 00:00 | Introducing K-Beauty Azelaic Acid Contenders 00:02 | The "Ouch" Factor: Testing medicube’s Needle Technology 00:04 | Sensation vs. Science: Do Spicules Improve Penetration? 00:05 | Texture…

About Chemist Confessions

Chemist Confessions is a English arts & books podcast from Chemist Confessions Inc.. Melo plays each episode straight from the publisher's own feed — no ads added, no account needed — and remembers where you stopped, in this browser only.

Publisher: Chemist Confessions Inc.
Language: English
Category: Arts & Books
New episodes: Weekly
Typical length: 39 min
Latest episode: 9 Oct 2026
Feed: RSS — paste into any podcast app
Apple Podcasts: podcasts.apple.com/podcast/id1481543700

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