Podcast · Learning
by Dave Asprey · English · Learning
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in b
8 Oct 2026 · 1 hr 4 minNew
Dave Asprey and psychic medical intuitive Julie Ryan explore whether intuitive abilities can be trained, how they may relate to healing and consciousness, and what Julie says happens as people approach death.
E1550 · 6 Oct 2026 · 52 minNew
Miranda Kerr joins Dave Asprey to explore how simplifying health around clean living, sleep, stress management, meditation, family, and intentional skincare can create a more sustainable approach to wellness.
E1549 · 4 Oct 2026 · 19 min
Dave Asprey shares the five hacks that helped him lose over 100 pounds and feel decades younger, from inventing butter coffee in Tibet to eating more saturated fat, cutting anti-nutrients, intermittent fasting, and prioritizing nutrition over endless gym sessions.
E1548 · 2 Oct 2026 · 11 min
Dave Asprey breaks down new research on vagus nerve stimulation and memory, feline cancer genetics, inherited cognitive ability, mulberries and the microbiome, and how magnesium changes vitamin D metabolism.
E1547 · 1 Oct 2026 · 47 min
The founders of Young Goose explore science-backed, longevity-focused skincare — covering metabolomic skin testing, key ingredients like ergothioneine and ectoin, mitochondrial dysfunction, vampire exosomes, red light therapy stacking, and proteomics — all aimed at targeting the 12 hallmarks of aging rather than just treating surface symptoms.
E1546 · 29 Sep 2026 · 57 min
Fatty Liver, GLP-1s, Alcohol, Hormones, Brain Fog, Weight Gain & Longevity
E1545 · 27 Sep 2026 · 14 min
Dave Asprey outlines six science-backed methods to melt visceral fat—ranging from high-protein eating and HIIT to cold exposure, weightlifting, quality sleep, and stress reduction—arguing that chronic stress is the root cause that must be addressed for lasting fat loss.
E1544 · 25 Sep 2026 · 15 min
A roundup of five health stories — Novo Nordisk's interest in hair loss, nutritional deficiencies in kids on GLP-1s, stomach-brain synchronization and mental health, food preservatives linked to heart disease, and taurine's stress-protective effects in rats — closing with a reminder to audit the hidden downsides of any health intervention you're already doing.
E1543 · 24 Sep 2026 · 1 hr 14 min
Dr. Robert Waldinger shares findings from the 85-year Harvard Study of Adult Development revealing that the quality of our relationships—not wealth, fame, or power—is the single greatest predictor of health, happiness, and longevity, and offers practical strategies for building "social fitness" at any life stage.
E1541 · 22 Sep 2026 · 59 min
Dave Asprey and Catharine Arnston explore how spirulina and chlorella may support mitochondrial function, cellular energy, detoxification, brain health, and healthy aging.
E1540 · 20 Sep 2026 · 21 min
A mold illness survivor explains how toxic mold in your home and body causes chronic brain fog, fatigue, and inflammation — and lays out a step-by-step plan to identify the source, remediate your environment, and detox what your body has already absorbed.
E1539 · 18 Sep 2026 · 1 hr 3 min
Dave Asprey sits down with spiritual teacher Teal Swan to explore narcissism, betrayal, extrasensory perception, the nature of ego, divine masculine and feminine energy, and whether humanity can heal its deepest wounds.
E1538 · 17 Sep 2026 · 54 min
Dave Asprey and neurobiologist Dr. Michael Leon explore how your sense of smell influences memory, sleep, brain aging, and longevity, and why olfactory enrichment may be one of the most overlooked tools for protecting cognitive health.
E1537 · 16 Sep 2026 · 56 min
This episode is a wide-ranging conversation covering testosterone and hormone replacement therapy, peptides, biohacking, psychedelics and spirituality, parenting, and building a health/longevity business, with the hosts sharing personal experiences throughout.
E1536 · 15 Sep 2026 · 56 min
Dave Asprey and Carolina Reis de Oliveira break down how senescent cells, menopause, hydration loss, and peptide science affect skin aging, and what the latest research suggests may help make skin function biologically younger.
E1535 · 13 Sep 2026 · 12 min
This episode walks through an hour-by-hour timeline of what happens in your body during 36 hours without sugar — from falling insulin and dwindling glycogen to fat burning, ketone production, autophagy, and hormonal reset — explaining how cutting sugar reverses insulin resistance and drives visible physical improvements.
E1534 · 11 Sep 2026 · 10 min
This week's biohacking roundup covers anti-aging plasmalogens from sea squirts, major new Apple Watch health-monitoring features (including passive hypertension detection), an FDA push to modernize botanical drug regulation, a study linking adolescent-onset cannabis dependence to cognitive decline, and a blueberry compound that may help muscle cells burn fat.
E1533 · 8 Sep 2026 · 1 hr 9 min
Dave Asprey and Dr. Karan Rajan dive deep into gut health, covering fiber science, fermentation, sodium myths, and the weirdest things a GI surgeon has ever removed from a patient.
E1532 · 6 Sep 2026 · 10 min
Dave Asprey breaks down three science-backed rules — cutting ultra-processed food, adopting adequate fasting windows, and redesigning your environment — to lower insulin resistance and break the metabolic block that's stalling your fat loss.
E1531 · 4 Sep 2026 · 8 min
This episode debunks some viral raw garlic claims and reviews new research on HEPA filtration, egg yolk peptides, heatstroke's long-term health risks, and melatonin's link to heart failure — closing with a reminder to control how much stress you put your body through.
E1530 · 3 Sep 2026 · 1 hr 58 min
Jenny McCarthy Wahlberg joins Dave Asprey to trace her son's autism diagnosis back to a vaccine reaction and share the detox, gut-healing, and biohacking protocol that reversed it, then dives into peptides, hormone therapy, and longevity strategies for adults.
E1529 · 1 Sep 2026 · 36 min
Dave Asprey breaks down why metformin, rapamycin, and statins fall short as longevity drugs, and makes the case for tadalafil, SGLT2 inhibitors, acarbose, and low dose naltrexone instead.
E1528 · 30 Aug 2026 · 10 min
can you give me a you'll learn section for this episode, similar to this one: You'll also learn: Why your body actively destroys NAD+ faster as you age, and why that's the real driver of fatigue and brain fog How the gap between NAD+ production and destruction widens every year, quietly draining your cellular energy The early signs your NAD+ levels are already too low, from slow-healing skin to workouts that take days to recover from What actually flips your body's NAD+ production back on, and the exact order of diet, fasting, exercise, and supplementation that makes it work Here's a "You'll…
E1527 · 28 Aug 2026 · 1 hr 14 min
Dave Asprey interviews Hal Elrod about his updated Miracle Morning book, weaving in candid tangents on diet, masculinity, cancer survival, and morning/evening routines for peak performance.
E1526 · 27 Aug 2026 · 1 hr 2 min
Jonny Miller joins Dave to unpack how nervous system mastery—interoception, self-regulation, and emotional fluidity—transforms grief, business setbacks, intuition, and relationships into sources of growth rather than reactivity.
E1525 · 25 Aug 2026 · 1 hr 2 min
Jim Kwik joins Host Dave Asprey to reveal how AI is quietly eroding human memory and critical thinking, and shares the framework for using it to sharpen your brain instead.
E1524 · 23 Aug 2026 · 15 min
Dave Asprey explains why declining NAD+ drives aging, fatigue, and cognitive decline, and lays out a diet, fasting, exercise, and supplementation protocol to rebuild it.
E1523 · 21 Aug 2026 · 36 min
Dave Asprey sits down with Gurudev Sri Sri Ravi Shankar for a wide-ranging conversation on curiosity, non-dual consciousness, breathwork's power to calm the mind, and using ancient wisdom to address modern problems like violence, disconnection, and fear.
E1522 · 20 Aug 2026 · 1 hr 3 min
Patrick Coles, a physicist and biochemist, makes the case that cancer tumors are the body's intentional toxin-storage vaults rather than random malignant growth, and that lowering your toxic burden, not just fighting the tumor itself, may be the real key to reversing it.
E1521 · 18 Aug 2026 · 2 hr 47 min
Dave Asprey and Gabby Reece swap interviews on biohacking, longevity, and mitochondrial health, then pivot into a candid conversation about fame, parenting, surrender, hormones, and finding peace through purposeful pursuit rather than achievement.
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
The Human Upgrade: Biohacking for Longevity & Performance is a English learning podcast from Dave Asprey. Melo plays each episode straight from the publisher's own feed — no ads added, no account needed — and remembers where you stopped, in this browser only.
The Melo app keeps playing with the screen off, works in the car and on your watch, wakes you to your station, and browses the whole catalogue offline. Free, no ads, no account.
